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DEPCS TA Lead, Ophthalmology

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Genentech
Full Time position
Listed on 2026-02-07
Job specializations:
  • IT/Tech
    AI Engineer, Data Science Manager
Job Description & How to Apply Below

The Position does not appear as a standalone description in this refined format. Below is a structured, job-focused refinement using allowed tags.

Overview

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is based in the Digital Endpoints and Patient-Centered Solutions (DEPCS) team, which is an innovative digital, AI, and tech function within Roche Product Development Data Sciences (PDD). DEPCS embeds patient-centered and AI-enabled digital solutions into clinical research by integrating data science, measurement science, and digital product thinking to deliver scalable and regulatory-ready innovations that enhance trial design, evidence generation, and clinical value of Roche medicines.

The

Opportunity

As the Therapeutic Area (TA) Lead for Ophthalmology within the Digital Endpoints and Patient-Centered Solutions (DEPCS) function, you will provide strategic direction and cross-functional leadership to advance digital, AI, imaging, and patient-centered strategies supporting the therapeutic area. You will act as the primary DEPCS partner to stakeholders in Clinical Development, Biostatistics, Regulatory, GPS, pRED, and gRED, ensuring digital and measurement strategies are aligned with program needs and embedded into development decision-making.

This role is critical to ensuring delivery of validated, scalable, and patient-relevant solutions, with a focus on late-stage development and regulatory readiness. You will lead TA-specific DEPCS planning, contribute to portfolio execution, and oversee cross-functional delivery in alignment with broader PD-DSA and Roche strategies.

  • You align digital, AI, imaging, and patient-centered strategies for Ophthalmology with Roche’s broader PD-DSA, One Pharma goals, and other enterprise-wide initiatives
  • You champion and integrate the 3

    Ds – Data, Digital/AI, and Design – into TA-level decision-making, product development, and clinical delivery
  • You act as a role model for digital health leadership by promoting scientific rigor, practical feasibility assessment, operational excellence, and a learning mindset
  • You ensure clear accountability and cross-functional alignment in the execution of TA-level innovation priorities
  • You provide strategic leadership for DEPCS within Ophthalmology, translating enterprise and functional priorities into TA-specific roadmaps and initiatives
  • You guide the integration of patient-centered solutions, digital endpoints, imaging algorithms, and AI capabilities into the drug development lifecycle
  • You align DEPCS strategy for Ophthalmology within cross-functional and enterprise governance frameworks, contributing to PD-DSA strategy execution
  • You anticipate scientific, regulatory, and technological trends and steer portfolio planning to maximize impact and value
  • You represent the TA in DEPCS and cross-functional forums, shaping investment cases, resourcing needs, and platform alignment
  • You influence decision-making in TA-level governance bodies (e.g., Development Boards) through delivery of validated and impactful digital innovations
  • You act as the single point of contact and DEPCS lead for Ophthalmology, ensuring cohesive and responsive engagement with Clinical, Regulatory, GPS, Biostats, pRED, and gRED
  • You build strong relationships with TA-aligned leaders across PDD to support seamless integration of digital, design, and data strategies into the therapeutic portfolio
  • You collaborate with DEPCS internal capability leads (Imaging, PCOR, AI/ML, Data Validation) to enable fit-for-purpose innovation
  • You foster partnerships with external collaborators (technology providers, academic institutions, regulators, and patient groups) to strengthen delivery and credibility
  • You ensure TA representation in DEPCS and PDD planning processes and advocate for TA-specific needs in functional strategies
  • You oversee assessment, validation, and implementation of DEPCS solutions across Ophthalmology, including digital endpoints, PROs/COAs,…
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