Research & Early Development Enterprise Architect

The Opportunity

Research & Early Development Architect is a strategic technology and organizational leader who operates at the intersection of scientific enablement, digital transformation, and digital strategy. In this role you will help shape and drive a modern enterprise architecture vision across Research & Early Development to enable a scalable and cohesive digital ecosystem that supports scientific innovation, seamless data integration, and AI-enabled discovery.

In this role, you will:

• Contribute to the definition and evolution of a modern enterprise architecture vision, including principles, governance, standards, and reusable patterns.
• Guide strategic technology and architecture decisions across Research & Early Development while balancing innovation, scalability, compliance, and operational sustainability.
• Influence and align senior stakeholders across scientific, business, and technology organizations to drive cohesive enterprise outcomes.
• Partner with leaders across the CoE, gRED, pRED, and Roche Informatics to support enterprise-wide collaboration and harmonization.
• Support transformation initiatives that modernize legacy ecosystems into modular, interoperable, and scalable digital platforms.
• Drive architectural thinking that enables seamless data flow, integration, automation, and AI/ML capabilities across the organization.
• Facilitate architectural governance and decision-making processes in a way that enables agility while maintaining enterprise alignment.
• Evaluate emerging technologies and architectural approaches to support future scientific and business needs.
• Contribute to the development of reference architectures, strategic roadmaps, and architectural guidance that support both current and future organizational priorities.
• Mentor and influence technical teams and architecture communities to foster collaboration, consistency, and technical excellence.

We are looking for a leader with the following qualifications and experience.

• You are an effective communicator and relationship builder who can engage confidently with both technical and non-technical stakeholders.
• You have demonstrated experience influencing senior leaders and driving alignment across complex, matrixed organizations.
• You are comfortable operating in environments with ambiguity, organizational change, and competing priorities.
• You act as a trusted advisor who can facilitate strategic discussions, challenge assumptions constructively, and help organizations make informed decisions.
• You have experience collaborating across multidisciplinary teams and fostering a culture of partnership, transparency, and continuous improvement.

• You can think holistically across business processes, data, applications, technology, and organizational capabilities.
• You understand how to balance long-term enterprise strategy with pragmatic delivery needs and organizational realities.
• You have experience supporting enterprise transformation initiatives in large and complex organizations.
• You are able to connect technology decisions to scientific, operational, and business outcomes.

• You hold a PhD + 6-13 yrs, MS + 8-16 yrs, or a BS + 11-18 yrs of relevant work experience in a scientific or technical field with 8+ years of experience (Senior Principal Engineer);
  PhD + >12 yrs, MS + >15, or BS + >17 yrs of relevant work experience (Enterprise Architect).
• You have experience in enterprise architecture, solution architecture, or related strategic technology roles within complex environments.
• You possess a strong understanding of modern enterprise and digital architecture concepts, including cloud, integration, data, and AI-enabled ecosystems.
• Experience in healthcare, life sciences, biotech, or regulated environments is preferred.
• Familiarity with modern architectural approaches and digital technologies is beneficial, including cloud platforms, distributed systems, data platforms, and modern software engineering practices.

Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week.

Relocation benefits are not available for this posting.

The…