Translational Research Scientist

Translational Research Scientist - II

Pay Rate: $85/HR on W2

Location:

213

E. Grand Avenue, South San Francisco, CA 94080

Required:

Web/software background must have been utilized within the IHC field, not looking for web design industry experience. Can be academic or industry experience. Should have:

• High level of comfort with histology/microanatomy strongly preferred
• Background in oncology and/or immunology
• Programming skills with application in imaging (e.g. Python, MATLAB) data
• Should be comfortable with histology, anatomy and IHC assay experience

Preferred:
Automation experience and image analysis a plus.

Qualifications:

• B.S with minimum 5+ years’;
  Masters with 3+ years’; PHD with 1-2 years’ of relevant work experience in industry or academia
• Experience with immunohistochemistry and multiplexed immunofluorescence assay development
• Experience using digital image analysis software and spatial imaging platforms such as HALO, Visiopharm, QuPath, digital slide scanning, multiplex spectral imaging, Akoya Polaris, Phenocycler/Fusion
• Strong organizational abilities and communication skills

Responsibilities:

The Anatomic Pathology group within the Profiling & Expression department is seeking a motivated, experienced scientist with experience in multiplexed immunofluorescence assay development and digital image analysis to support discovery and translational research in our pathology group in South San Francisco.

The successful candidate will:

• Perform validation and quality check of the analysis readout on multiplexed immunofluorescence images
• Perform image preprocessing tasks according to established SOPs, including metadata extraction, output quality control, and secure data transfer to cloud storage
• Assist in evaluating and implementing new algorithms to enhance the image analysis pipeline, such as cell segmentation improvements, tissue classification, and cell phenotyping
• Assist with the transfer of data and image-related information for analysis, facilitating smooth collaboration between teams
• Coordinating with IT to:
• Gather and document feedback from users on image analysis workflows and tools
• Address user pain points, define requirements, and improve tool functionality
• Lead user experience testing, working with IT to implement improvements and optimize tools for production use
• Maintain and update image analysis computers to ensure they remain optimized for routine tasks
• Define and document requirements for new tools and ensure their successful deployment
• Provide administrative support for multiplex IHC related work, including reagent ordering, capital equipment purchasing, document and maintain SOPs for image processing and analysis workflows
• Interact smoothly with scientists, computer scientists, and informatics/IT staff, both internally and externally