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Senior Principal Engineer, Infrastructure Lead

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Bridge Analytics
Full Time position
Listed on 2026-08-22
Job specializations:
  • IT/Tech
    Cloud Computing: Infrastructure & Operations, Cybersecurity
Salary/Wage Range or Industry Benchmark: 180000 - 280000 USD Yearly USD 180000.00 280000.00 YEAR
Job Description & How to Apply Below

Senior Principal Engineer, Infrastructure Lead

Bridge Analytics is seeking a senior, security-minded infrastructure leader to own the cloud foundation of the Bridge Analytics Environment (BAE) — a Trusted Research Environment on Google Cloud Platform that gives the world’s leading neuroscientists secure, fully-audited access to harmonized, multi-modal data with native compute. In this role, you will own the infrastructure, reliability, and security perimeter that let BAE scale to 500+ external researchers at public launch and across a growing multi-study portfolio advancing science and therapeutics for Parkinson’s disease, autism, and bipolar disorder.

This is a senior individual-contributor role. You set the technical direction and build hands-on, backed by contractor and consultant resources for implementation, operations, and help desk — so you multiply your impact without building or managing a large team. You will operate in a fast-scaling, security-first environment where the perimeter is non-negotiable and everything must be reproducible and auditable. We are looking for a true owner who can codify a live platform into infrastructure-as-code and set the reliability and security bar for the whole environment.

Key Responsibilities
  • SDLC & Delivery Backbone: Establish parity dev, test, and production environments with CI/CD (Cloud Build, Git Hub Actions) on our infrastructure-as-code (CDKTF/Terraform for Python), deploying reliably across GCP projects for both internal data operations and external researchers.
  • Reliability & Operations: Define SLOs/SLIs and build the observability, alerting, incident response, and runbooks for live researcher workloads — with a light on-call rotation supported by contractor resources — and retire single points of failure so the platform is dependable at 500+ users.
  • Security & Perimeter Ownership: Own and harden the security perimeter — VPC Service Controls, Assured Workloads, organization policy, and least-privilege IAM — along with the exfiltration posture (full and controlled exfiltration prevention, geo-blocking) and forensic audit logging that keep a regulated TRE demonstrably safe.
  • Identity & Access: Automate the access and permissions lifecycle — group-based RBAC and provisioning via Cloud Identity and OIDC federation — to replace manual work and scale researcher onboarding through beta and launch.
  • Scaling the Portfolio: Templatize per-project GCP provisioning so every new study in a growing multi-study portfolio lands in an isolated, properly-configured project instead of bespoke setup each time.
  • Direct Contractor & Consultant Support: Set direction for the contractor and consultant resources that help with implementation, operations, and help desk — reviewing for quality and security and ensuring every change lands in our repos and runbooks — and partner with IT and Compliance on HIPAA/GDPR-aligned controls.
Who You Are
  • You have deep, hands-on experience building and operating production cloud at scale, and the seniority to set the technical bar for an entire platform — not just a single service.
  • You thrive as a hands-on individual contributor — you would rather set direction and build than manage a large team, and you know how to get leverage from contractor and consultant resources.
  • You treat security as non-negotiable and can own a regulated perimeter end-to-end, from VPC Service Controls and IAM to DLP and complete audit logging.
  • You are a force multiplier: you turn tribal knowledge into infrastructure-as-code and runbooks, and you direct contractor and consultant resources rather than carrying every ticket yourself.
  • You don’t wait to be told what to do; you proactively anticipate failure modes and retire single points of failure before they become incidents.
  • You are eager to adopt and integrate modern AI tools into your daily workflow to multiply your impact — this is an AI-native team.
  • You care about the mission and want your work in researchers’ hands in weeks, not years.
Qualifications

Minimum Qualifications:
  • Experience: 10+ years in infrastructure, platform, or Site Reliability Engineering roles, operating production cloud at scale.
  • Google Cloud Platform: D…
Position Requirements
10+ Years work experience
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