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Director​/Senior Director, Analytical Methods (Methods4Insight

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: BioSpace
Full Time position
Listed on 2026-08-22
Job specializations:
  • IT/Tech
    Data Scientist, AI Engineer (Applied/Software), Data Analyst, Data Engineering
Salary/Wage Range or Industry Benchmark: 194000 - 339000 USD Yearly USD 194000.00 339000.00 YEAR
Job Description & How to Apply Below
Position: Director/Senior Director, Analytical Methods (Methods4Insight)

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve.

This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Location:

San Francisco, CA;
Louisville, CO;
Indianapolis, IN

Reports to:

AVP - Methods4

Insight, Data Foundry Overview

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Lilly Small Molecule Discovery

is an organization purpose-built to create molecules that make life better for people. We focus on using cutting edge science to unlock new approaches that can treat people suffering from diseases with poor treatment options. We continually challenge ourselves to deliver molecules that can provide breakthrough efficacy with the highest possible safety margins. We are dedicated to optimizing our mindset, technology, and processes for faster, more nimble execution.

We are dedicated to optimizing our mindset, technology, and processes for faster, more nimble execution.

Discovery Technology and Platforms

is a newly established function within this organization. Its mission is to accelerate molecule discovery by building highly optimized foundational platforms, streamlining lab operations through advanced technologies and data connectivity, and intentionally investing in novel technologies and capabilities.

About Data Foundry

Data Foundry is a multidisciplinary team dedicated to enabling and accelerating molecule discovery through scalable and reproducible data generation, fueled by advanced scientific computing, informatics, and automation solutions. Data Foundry operates through four integrated pillars:
Architecture4

Insight
(data infrastructure and scientific software),
Methods4

Insight
(analytical and computational methods),
Scale4

Insight
(lab automation and agentic workflows), and Preparedness4

Insight
(data governance and readiness). Together, these pillars empower every Lilly scientist to make optimal decisions by providing seamless access to data, insights, and AI-driven capabilities at scale.

Position Summary

The Director/Senior Director, Analytical Methods will serve as a domain expert and technical leader within Methods4

Insight, responsible for developing, deploying, and maintaining cutting-edge analytical approaches in their area of expertise — such as cheminformatics, computational structural biology, statistical modeling, or AI/ML. This role combines deep domain knowledge with scientific leadership, translating advanced methods into practical capabilities that accelerate molecule discovery for both human scientists and autonomous AI agents.

You will work alongside discovery project teams and supporting functions to understand scientific challenges, provide expert consultation, and develop custom solutions when existing methods fall short.

You will maintain awareness of emerging methods, evaluate their value, and make informed build-versus-buy-versus-adopt recommendations.

You will collaborate closely with Methods4

Insight domain experts, Architecture4

Insight, Scale4

Insight, and Frontier AI.

We're looking for someone who is recognized as an expert in their analytical domain, has a strong publication record, has deployed methods that influenced real discovery decisions, and is passionate about advancing their field and enabling scientific impact.

What You'll Do
  • Serve as the subject matter expert in your analytical domain, staying current on innovative…
Position Requirements
10+ Years work experience
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