Global Manufacturing & Supply Chain Exec – Launch Readiness

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February of 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

POSITION SUMMARY
As we continue to advance our innovative product pipeline and progress our lead obesity development program towards commercialization and launch, we are seeking a Vice President, Global Manufacturing & Supply Chain reporting to the SVP of Technical Operations to lead our end-to-end manufacturing, supply chain and commercial readiness activities. As a strategic and results-oriented senior leader within Technical Operations, this individual will be responsible for building a high performing manufacturing and supply chain function and establishing the necessary organization, business processes and systems required to ensure reliable and efficient product global supply and commercial launch readiness.

This role requires deep expertise in small molecule pharmaceutical operations, an understanding of the pharmaceutical product development lifecycle, excellent business acumen and the ability to thrive in a dynamic, fast-paced environment. Excellent communication skills are a must for this multidisciplinary and global effort.

KEY RESPONSIBILITIES
External Manufacturing

• Develop and lead the external manufacturing strategy across DS, DP, and packaged/finished product to support global clinical trials and commercial supply.
• Establish external manufacturing team, process, governance, KPIs, working agreements and business review cadence with partnership mindset and monitor execution and ongoing production performance.
• Ensure reliable execution of manufacturing operations to meet PDUFA, launch, and ongoing supply needs—including campaign planning, batch release, and issue resolution.
• Lead CDMO governance and relationship management, including executive-level interactions, KPIs, and escalation pathways.
• Serve as the executive leader and primary point of accountability for CDMO performance, including quality, timelines, cost, and compliance.
• Partner with Quality and Regulatory to ensure GMP compliance, inspection readiness, and alignment with global regulatory expectations.
• Collaborate cross-functionally with CMC Development, Quality, Supply Chain, and Regulatory to align on technical transfers, validation strategies, and lifecycle management.
• Proactively identify risks and implement mitigation plans to ensure continuity and robustness of external manufacturing operations.
• Provide strategic input into make/buy decisions, site selection, and future-state network design.
• Support business development and sourcing efforts related to manufacturing. Lead CDMO strategic sourcing and selection efforts from needs definition to RFP to selection and start-up to secure the necessary CDMO capabilities and capacities to meet all product supply needs.

Global Supply Chain and Commercial…