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Research Scientist – Automation and -throughput antibody screening

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: WorkLlama, Inc.
Full Time position
Listed on 2026-02-16
Job specializations:
  • Research/Development
    Research Scientist, Clinical Research, Biomedical Science
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below
Position: Research Scientist – Automation and High-throughput antibody screening

We are seeking a highly motivated Research Scientist to join our Lab Automation Team within the Antibody Discovery group. This role is a key contributor to an innovative program focused on modernizing and automating antibody discovery workflows to meet strategic organizational goals. The successful candidate will support and optimize hybridoma-based antibody generation using advanced automation equipment and streamlined data processing to produce robust data packages.

You will be responsible for designing, automating, and executing cell- and protein-based screening and characterization assays in a fast-paced, multidisciplinary environment.

Responsibilities
  • Design, implement, and validate automated methods for high-throughput antibody screening and characterization.
  • Perform general laboratory research independently, modifying and troubleshooting experimental designs and instrumentation as needed.
  • Support the expansion of high-throughput screening (HTS) platforms and the integration of novel technologies.
  • Implement automated liquid handling processes for routine workflows, including protein normalization, serial dilution, and NGS library preparation.
  • Maintain and perform cell culture on various cell types to support the characterization of antibodies and biologics.
  • Analyze and interpret experimental results, placing findings in scientific context through literature review.
  • Document and report data clearly, preparing presentations for team and project meetings.
  • Collaborate effectively with cross-functional partners to manage multiple projects simultaneously.
  • Adhere to good laboratory practices (GLP) and ensure compliance with all safety and quality standards.
Education
  • Bachelor’s degree in Biology, Molecular Biology, Biochemistry, Immunology, Biotechnology, or a related scientific discipline.
  • BS with 3–5 years of relevant experience, or a Master’s degree (preferred).
Experience
  • Assay Expertise:
    Strong hands-on experience with binding assays (ELISA, flow cytometry/FACS) and antibody functional characterization.
  • Automation:
    Proven experience with automated liquid handling platforms (e.g., Hamilton Microlab STAR) and robotic arms.
  • Cell Culture:
    Demonstrated proficiency in mammalian cell culture techniques, including maintenance and expansion.
  • Project Management:
    Experience independently planning experiments, troubleshooting, and managing multiple concurrent laboratory tasks.
  • Technical Tools (Preferred):
    Familiarity with microplate readers (Spectra Max, EnVision) and programming/scripting (Python, SQL, Venus, or Momentum) for workflow automation.
Additional Information
  • Technical Proficiency:
    Must be skilled in scientific data analysis software such as Graph Pad Prism, Spotfire, or Genedata.
  • Logistics:
    This role requires the ability to adapt to rapid changes in project priorities and timelines while maintaining high attention to detail.
  • Teamwork:
    Candidates must demonstrate excellent communication skills and a proven ability to operate as a team player in a high-energy, multi-disciplinary setting.
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