Associate Scientist II, Biologics Drug Product Development

Company Description

Abb Vie’s mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas—immunology, oncology, neuroscience, and eye care—and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  Follow @abbvie on X, Facebook, Instagram, You Tube, Linked In and Tik Tok.

The Biologics Drug Product Development group within Abb Vie is a global organization responsible for developing and characterizing drug product formulations and manufacturing processes for biologic therapeutics (antibodies, antibody-drug conjugates (ADCs), neurotoxins, and novel biologic formats) from preclinical development through clinical proof of concept. We have an exciting opportunity available for an Associate Scientist II to join our team at our Bay Area site in South San Francisco, CA.

This is a lab-based position and requires full‑time on‑site presence. Successful candidates will thrive in a collaborative lab environment.

• Own & support stability / in‑use / process studies: work within the process operations team to fill development drug product batches for GLP toxicology studies, reference standard fills, and representative drug product batches. Develop skills to plan and execute screening, in‑use, and formulation stability studies to support formulation and process development for clinical trials.
• Perform analytical assays & support troubleshooting: conduct analytical assays to evaluate protein and excipients stability (i.e. HPLC/UPLC, SEC, CEX, CE‑SDS, icIEF, UV‑Vis, CD, Karl Fischer titration, HIAC, MFI). Generate high‑quality data to support selection of formulation composition, development of dose administration guidance, and drug product manufacturing instructions. Develop the skills to independently troubleshoot assays and instruments to ensure consistent quality data output.
• Analyze & communicate results: analyze study results, organize and document the results in an electronic lab notebook (ELN), and effectively communicate updates, troubleshooting, and results to the team. Interpret results and draw conclusions from multistage experiments with support from study owners and project leads. Communicate aberrant data and lab issues to management to gain input and alignment on solution.
• Write technical reports and communicate technical updates: author technical reports to support regulatory filings and present the study results and findings to the team.
• Collaboration: collaborate closely with highly matrixed team members to support pipeline programs and participate in project teams as a study owner.

• Degree in chemistry, chemical engineering, biochemistry, pharmaceutical sciences or equivalent
  • Bachelor’s Degree with 3 or more years’ experience or Master’s Degree (no additional experience)
• Strong technical background encompassing protein chemistry and protein handling.
• Hands‑on experience with running and troubleshooting analytical techniques used for protein characterization and stability testing such as SEC, CEX, iCIEF, CE‑SDS, HIAC, and MFI.
• Ability to work in cross‑matrixed team supporting multiple projects and participate in project‑focused teams.
• Technical ability to execute and troubleshoot experiments through rational and critical thinking. Must be highly organized and detail oriented.
• Eagerness to learn and apply new scientific techniques.
• Excellent verbal and written communication skills.
• Strong collaborative skills for working effectively within the team.
• Prior experience in protein formulation development, process development, drug delivery, or analytical functions is highly preferred.
• Prior experience utilizing automated liquid handlers and/or executing high‑throughput screening workflows is highly preferred.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay…