Associate Principal Scientist, Antibody Discovery Innovation

** Job Description
** We are on a quest for cures and are committed to be the world’s premier, most research-intensive biopharmaceutical company. Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines.

We are seeking an exceptional and experienced scientist in the role of Associate Principal Scientist in the South San Francisco Discovery Biologics group. The qualified candidate will be a scientist with a breadth and depth of expertise in immunization-based antibody discovery, including but not limited to expertise in adaptive immunity and B-cell biology, immunogen design, and experience with multiple hit finding platforms (e.g. high throughput microfluidics & NGS), in order to improve existing antibody discovery processes to help meet the needs for challenging targets and aggressive timelines.

They will work closely with other team members and groups throughout the organization to help manage, perform, and troubleshoot antibody discovery programs.

We recognize that our team is our strength, and we are committed to creating an inclusive environment for all employees. Successful candidates must demonstrate inclusive behaviors in working with a group of researchers to drive our core mission.
*
* What you will do:

*** Propose and lead technology development initiatives for in vivo de novo antibody discovery to increase hits and decrease timelines
* Serve as the antibody discovery representative on project teams to help define Target Candidate Profiles (TCP) and lead de novo hit finding strategies and campaigns
* Stay abreast of external advancements in relevant scientific and technology fields
* Promote the external reputation of our company’s Discovery Biologics department
** What you will need to be successful in this role:
***
* Education:

*** Master's (with 8+ years) or Ph.D. (with 4+ years) in biophysics, biochemistry, structural biology or related science discipline and relevant industry experience
** Required

Experience and Skills:

*** Experience in antibody drug discovery supporting therapeutic programs
* Depth of knowledge in adaptive immunity and B-cell biology
* Track record of driving scientific and platform innovations
* Experience leading therapeutic antibody discovery campaigns
* Strong hands-on laboratory skills, including but not limited to cell culture, molecular biology, assay development, and flow cytometry
* Established external reputation through publications, presentations, and/or scientific community engagement
* Excellent communication and collaboration skills
* Ability to manage multiple projects simultaneously
** Preferred

Experience and Skills:

*** Ideal candidate will have experience in protein therapeutics beyond traditional mAbs including alternative non-Ig scaffolds, bi- or multi-specifics, fusion proteins, and ADCs#EligibleforERP
*
* Required Skills:

** Antibody Discovery, Antibody Drug Conjugates (ADC), Assay Development, B Cells, Biochemistry, Cell Cultures, Flow Cytometry, Immune Response, Immunizations, Microbiology, Microfluidics, Molecular Biology, Proteins, Structural Biology
** Preferred

Skills:

** Current Employees apply

Current Contingent Workers apply
** US and Puerto Rico Residents Only:
** Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please  if you need an accommodation during the application or hiring process.

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics.  As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities.  

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