Senior Research Scientist, Cancer Biology

Senior Research Scientist, Cancer Biology

We are seeking a highly motivated, independent PhD scientist with strong laboratory expertise to contribute to advancing the understanding of target biology and the mechanisms of action of novel small molecule inhibitors for cancer treatment. The Senior Research Scientist, Cancer Biology will focus on designing and executing cell-based studies to address critical scientific questions that support therapeutic development efforts. The ideal candidate is passionate about cancer biology, thrives in a fast-paced and collaborative environment, and is driven to contribute to the discovery and development of innovative oncology therapeutics.

Industry
:
Discovery and Development

Location
:
South San Francisco, CA

Compensation
: $65-$75 per hour (based upon experience)

Type
:
Full-time (12-month Contract, possibility of extension based on performance)

• Independently design and execute experimental studies
• Conduct in vitro and cell-based assays to investigate mechanisms of action for potential anti-cancer agents and identify novel biomarkers
• Analyze and interpret experimental data, and independently troubleshoot technical challenges
• Collaborate closely with research and project team members to align efforts with key scientific objectives
• Present findings and provide project updates at individual, team, and cross-functional meetings

• PhD in cancer biology, cell biology, molecular biology, or a related discipline, with 2–3 years of relevant experience; biotech or pharmaceutical industry experience preferred
• Background in cancer epigenetics and gene regulation is preferred; experience with ATAC-seq, CUT & RUN, bulk RNA-seq, or single-cell RNA-seq is a plus
• Hands‑on experience designing and performing flow cytometry assays
• Demonstrated commitment to rigorous, innovative laboratory research
• Strong attention to detail and enthusiasm for translating basic science insights into drug discovery strategies
• Extensive experience with mammalian cell culture and aseptic technique, including cell‑based assays assessing viability and function using siRNA, shRNA, CRISPR, and over-expression systems
• Proficiency in protein analysis methods such as Western blot, MSD, and ELISA, and gene expression analysis including qRT-PCR and RNA‑seq
• Ability to independently develop, optimize, and troubleshoot mechanism of action assays; experience collaborating with CROs is a plus
• Experience with bioinformatics data analysis and visualization is advantageous
• Strong organizational skills with the ability to manage multiple projects and shifting priorities
• Excellent communication and interpersonal skills, with the ability to engage cross-functional teams and lead scientific discussions

Estimated Min Rate
: $65.00

Estimated Max Rate
: $75.00

Benefits include:

• Medical, Prescription, Dental & Vision Benefits (for employees working 20+ hours per week)
• Health Savings Account (HSA) (for employees working 20+ hours per week)
• Life & Disability Insurance (for employees working 20+ hours per week)
• Met Life Voluntary Benefits
• Employee Assistance Program (EAP)
• 401K Retirement Savings Plan
• Direct Deposit & weekly epayroll
• Referral Bonus Programs
• Certification and training opportunities

Note:

Any pay ranges displayed are estimations. Actual pay is determined by an applicant's experience, technical expertise, and other qualifications as listed in the job description. All qualified applicants are welcome to apply.

Yoh, a Day & Zimmermann company, is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.

Visit to contact us if you are an individual with a disability and require accommodation in the application process.

For California applicants, qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. All of the material job duties described in this posting are job duties for which a criminal history may have a direct, adverse, and negative relationship potentially resulting in the withdrawal of a conditional offer of employment.

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