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Principal Scientist, Peptide Therapeutics: Lead Synthesis

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: F. Hoffmann-La Roche AG
Full Time position
Listed on 2026-07-25
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Pharmaceutical Science/ Research, Data Scientist
Salary/Wage Range or Industry Benchmark: 143200 - 265900 USD Yearly USD 143200.00 265900.00 YEAR
Job Description & How to Apply Below

Genentech, a member of the Roche group, seeks a Principal Scientist, Medicinal Chemist to lead lab-based peptide therapeutic discovery. You will drive synthesis, analytical rigor, and computational design while mentoring junior scientists.

Ideal candidates hold a PhD in Organic or Medicinal Chemistry with 3+ years postdoc/industry experience and have deep expertise in SPPS, macrocyclization, and structure-based design. Relocation benefits are available, and a discretionary annual bonus may apply.

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