Research Associate (HPLC | Biologics | AAV

Job Duration: 6 months Contract (Possibility of extension)

The primary responsibilities of the Biophysical Assay Research Associate will include performing analytical method development and testing samples using RP and SEC HPLC and other analytical tools; contributing to design and performing experiments with supervision as needed; completing assigned tasks within time frames with high quality; maintaining a well-documented record of activities in lab notebook and reports. The position level will be commensurate with education and experience level.

Additionally, the role includes regularly summarizing and presenting experimental results in lab meetings and responsible for generating reports. This role will be at our South San Francisco location.

• Conducting experiments to characterize adeno associated viral nanoparticles for gene therapy products.
• Performing assays for particle/protein/DNA in multiple assays including RP and SEC – HPLC methods to assist in evaluation of process change, formulation study, stability study using statistical methods as needed, following SOPs and execute experiments according to guidelines
• Developing new assays and transfer to QC, Process Development and Research.
• Developing new analytical tools to characterize adeno associated viral nanoparticles for gene therapy products.
• Participating in writing, reviewing, and editing experimental procedures and reports
• Maintaining accurate records of all analytical development activities timely.
• Analyzing and determining the applicability of laboratory data to draw conclusions and to make appropriate recommendations.

• Bachelor of Science with 1+ year experience working in a pharmaceutical or biotech company and with the requisite years’ of experience and with the requisite years’ of experience employing the skills listed in the job description (for each level) performing multiple assays for AAV, proteins and DNA.
• Successful experience in HPLC or other technologies for protein/DNA based product development
• Strong knowledge of Protein and DNA chemistry.
• Knowledge and proven experience in protein-based product development and characterization.
• Knowledge and expertise in principles and practice of current Good Manufacturing Practices (cGMP).
• Proficient in Microsoft Office to include Excel, PowerPoint, Word.
• Demonstrated verbal and written skills in technical reports and documents.
• Positive, professional self-starter with a passion for science.
• Proven ability to work collaboratively in a team environment as well as being an individual contributor.
• Models our Core Values:
  Be Bold:
  Find a Way, Care Deeply, Get Stuff Done – is experienced as someone who exemplifies the culture we want to create; operates with transparency; is trusted.