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Scientist II - Viral Vector

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Doist
Full Time position
Listed on 2026-08-06
Job specializations:
  • Research/Development
    Research Scientist
  • Healthcare
Salary/Wage Range or Industry Benchmark: 65 USD Hourly USD 65.00 HOUR
Job Description & How to Apply Below

Our client, a world leader in biotechnology and life sciences, is looking for a “Scientist II - Viral Vector” based out of South San Francisco, CA (Hybrid).

Rate: $65/hr on W2 (DOE) Job Duration:
Long-Term Contract (Possibility Of Extension)

Company Benefits
  • Medical
  • Dental
  • Vision
  • Paid Sick Leave
  • 401K
Summary

We are seeking a highly motivated Viral Vector Research Associate/Scientist with 5-10 years of laboratory research experience to support our Viral Vector Core and gene therapy research programs. The ideal candidate will have hands-on experience in viral vector production, mammalian cell culture, molecular biology, and CRISPR genome editing technologies. This role involves the production and characterization of lentiviral and AAV vectors, supporting next-generation viral vector engineering, maintaining viral inventories, and collaborating with cross-functional research teams to advance innovative gene therapy platforms.

Key Responsibilities
  • Produce, purify, and characterize lentiviral libraries and Adeno-associated virus (AAV) vectors to support research and preclinical studies.
  • Perform viral vector analytics using molecular biology techniques including PCR, qPCR, ddPCR/dPCR, Western blot, and related assays.
  • Maintain and manage viral vector inventory, sample tracking, and documentation using electronic laboratory notebooks (ELN) and digital informatics systems.
  • Support the engineering, optimization, and development of next-generation viral vectors and emerging viral-based therapeutic modalities.
  • Perform mammalian cell culture, transient plasmid transfection, cloning, and other molecular biology techniques.
  • Participate in CRISPR/Cas9 genome editing experiments for both in vitro and in vivo applications.
  • Operate laboratory instrumentation including flow cytometers and support data collection, analysis, and interpretation.
  • Maintain accurate laboratory documentation, experimental records, and inventory following established laboratory procedures.
  • Collaborate with multidisciplinary research teams to support gene therapy, virology, and genome engineering projects.
  • Analyze experimental data, troubleshoot protocols, and contribute to continuous process improvements.
Required Qualifications
  • MS or PhD in Cell Biology, Molecular Biology, Virology, Biochemistry, Bioengineering, Genetics, or a related scientific discipline.
  • 5-10 years of laboratory research experience in molecular biology, virology, or gene therapy.
  • Hands-on experience with lentiviral vector production and/or AAV production.
  • Strong experience with mammalian cell culture and transient plasmid transfection.
  • Experience with molecular biology techniques including: PCR, qPCR, ddPCR / dPCR, Western Blot.
  • Experience with CRISPR/Cas9 genome editing technologies.
  • Strong organizational, analytical, troubleshooting, and communication skills.
Preferred Qualifications
  • Experience with viral vector engineering and next-generation viral modalities.
  • Experience operating flow cytometers.
  • Familiarity with electronic laboratory notebooks (ELN) and digital sample management systems.
  • Experience with data analysis, computational programming, and bioinformatics tools.
  • Previous experience supporting gene therapy, viral vector core facilities, or translational research programs.
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