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Sr. Scientist

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Veracyte, Inc.
Full Time position
Listed on 2026-08-16
Job specializations:
  • Research/Development
  • IT/Tech
Salary/Wage Range or Industry Benchmark: 150000 - 170000 USD Yearly USD 150000.00 170000.00 YEAR
Job Description & How to Apply Below

At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a purpose driven environment. This is what we call the Veracyte way – it’s about how we work together, guided by our values, to give clinicians the insights they need to help patients make life-changing decisions.

Our

Values
  • We Seek A Better Way:
    We pursue bold ideas, embrace complexity, and keep pushing forward.
  • We Make It Happen:
    We act with urgency, deliver with excellence, and always find a way.
  • We Are Stronger Together:
    We engage with empathy, align around what's best for Veracyte, and celebrate as one team.
  • We Care Deeply:
    We show up with integrity, kindness, and respect for one another.
The Position

We are seeking an experienced Senior Scientist to lead the development of next-generation MRD assays from concept through clinical lab implementation. This individual will drive technical strategy, experimental design, and scientific decision-making across assay development, automation, and workflow optimization. The ideal candidate has direct experience in NGS-based oncology diagnostics and a proven track record of developing clinical assays in regulated environments through cross-functional leadership and scientific innovation.

Responsibilities
  • Lead the development, verification, and transfer of NGS-based MRD assays from concept through clinical lab implementation.
  • Independently develop workflows suitable for clinical operations, including automation, QC, throughput requirements, and LIMS integration.
  • Conceive innovative solutions and develop rigorous experimental strategies to advance assay performance, sensitivity, robustness, scalability, and operational readiness.
  • Design and execute feasibility, optimization, and verification studies, with independent ownership of objectives, study design, planning, execution, and analysis guided by systematic application of biochemistry and bioinformatic principles.
  • Author and review protocols, SOPs, reports, requirements, risk assessments, and design control documentation supporting product development and regulatory compliance.
  • Serve as a subject matter expert in NGS, oncology genomics, and ctDNA/MRD technologies, leading troubleshooting and resolution of complex technical challenges.
  • Collaborate cross-functionally with Bioinformatics, Data Science, Operations, Clinical Laboratory, Automation, SW/LIMS, Quality, and Regulatory teams to develop and implement robust diagnostic products.
  • Support technology transfer, assay implementation, and commercialization activities, including training and mentoring laboratory personnel and junior scientists.
Who You Are
  • NGS assay expert with deep theoretical and hands-on knowledge of the biochemistry underlying multi-component molecular biology methods at the sample preparation and assay level. Has a track record of successfully troubleshooting and optimizing molecular biology techniques/assays in a developed workflow.
  • Bench scientist eager to participate directly in laboratory work independently and in cooperation/coordination with others. Must be able to mentor others and effectively manage (design, monitor, complete, troubleshoot) laboratory project tasks performed in the hands of others.
  • Rigorous and skilled in NGS data analysis, with command of common and assay-specific metrics and excellent data analysis and visualization skills using common statistical methods and software (JMP, R, Python).
  • Successful product developer with experience writing requirements and systematically building products under global PDP.
  • Innovative technical leader eager to tackle complex scientific programs and generate solutions to challenging technical problems.
  • Team player who elevates performance within and across functions through technical collaboration, mentorship of junior scientists, and positive attitude.
  • Practical developer with the ability to evaluate multiple technical variables and translate data into actionable decisions that…
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