Associate Scientist - In Vivo Pharmacology, Oncology

** Join Amgen's Mission of Serving Patients*
* At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas
-Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

** Associate Scientist - In Vivo Pharmacology, Oncology*
* ** What you will do*
* Let's do this. Let's change the world. In this vital role you will work onsite at Amgen's South San Francisco campus as part of a fast-paced, integrated, and collaborative in vivo research team exploring therapeutics for oncology programs. You will be responsible for generating and communicating in vivo pharmacology data to support the progression of innovative oncology and immunotherapy research programs.

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* Key Responsibilities:

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* + Carry out hands-on in vivo work in mice, including handling, tumor inoculation and measurement, dosing (oral, SC, IP, and IV), blood and tissue collection, and health monitoring.

+ Perform necropsies and support ex vivo tissue activities, including dissection, processing, sample preparation, and experimental readouts.

+ Perform in vitro work including multiparametric flow cytometry and molecular biology techniques associated with in vivo studies.

+ Strong communication to support study execution, maintain accurate study records, and present results.

+ Active participation and presentation at cross-departmental teams and meetings

+ Participate in dosing rotations, including occasional evening or weekend work.

** What we expect of you*
* We are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a highly motivated and proactive researcher who wants to contribute to cutting edge science and serve patients with these qualifications.

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* Basic Qualifications:

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* Master's degree and 2+ years of experience in  _in-vivo_  work with rodents

OR

Bachelor's degree and 4+ years of experience in  _in-vivo_  work with rodents

OR

High school diploma / GED and 6 years of experience in  _in-vivo_  work with rodents

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* Preferred Qualifications:

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* + M.S. degree in Oncology, Biology, or related disciplines, or B.S. degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.

+ Hands-on experience with  _in-vivo_  models of cancer in an academic or industry setting and experience in pharmacology.

+ Proficiency in various mouse techniques such as dosing, in vivo PK/PD/Efficacy, health monitoring, blood and tissue collection, preferably for small molecule oncology therapeutics.

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Experience with PDX models of cancer.

+ Hands-on experience with  _in vivo_  bioluminescence imaging (BLI)

+ Flow cytometry and multi-parametric analysis experience is strongly desired.

+ Hands-on experience with molecular, cellular, and  _ex vivo_  biological techniques and assays

+ Computer literacy and proficiency with Graph Pad Prism, Excel, PowerPoint, Word and scientific software.

+ Attention to detail, excellent organizational and communication skills, accurate & timely record keeping and data analysis.

+ Pro-active, enthusiastic, show desire to learn and be part of a highly productive team.

** What you can expect of us*
* As we work to develop treatments that take care of others, we also work to care for your professional and personal…