Senior Director, Health Economics and Outcomes Research ​/ Real World Evidence

Position Summary

We are seeking a Senior Director of Health Economics and Outcomes Research / Real World Evidence (HEOR/RWE) to join the IDEAYA Commercial team. The Senior Director will shape and execute the health economics, outcomes research, and real‑world evidence strategy for the launch of darovasertib in metastatic uveal melanoma (mUM) and will later contribute to the global launches of IDEAYA’s oncology pipeline.

Location:

South San Francisco, CA. Position is based in the South San Francisco headquarters and requires onsite presence four days per week in accordance with company policy.

Reporting to:
Vice President, Value and Access.

• Develop and execute the HEOR and RWE strategy to support US value demonstration for darovasertib at launch and through its lifecycle.
• Collaborate with Market Access, Medical Affairs and Clinical Development to evaluate data gaps and develop robust evidence generation and publication plans.
• Plan and conduct core evidence‑generation activities, including chart reviews, literature reviews, PRO studies, and micro‑costing analyses to strengthen the clinical and economic differentiation of the product.
• Design and implement real‑world data analyses to articulate current patient demographics, treatment patterns, and outcomes for mUM patients.
• Develop comprehensive health economic model analyses to demonstrate value, inform pricing strategy, and support reimbursement decisions.
• Partner with Market Access to develop robust and compelling clinical, humanistic, and economic value propositions and oversee development of AMCP and Global Value Dossiers.
• Lead the external dissemination of HEOR/RWE deliverables, including publications, presentations, and professional conferences.
• Develop, train, and implement the resources that support field HEOR efforts with key customers, ensuring programs and materials comply with SOPs and Medical, Legal & Regulatory (MLR) reviews.
• Engage and collaborate with external partners—including payers, providers, and other access decision‑makers—to establish and maintain strong partnerships and gather insights.
• Support field team engagements during Pre‑approval Information Exchange (PIE) and post‑approval interactions to educate payers and provider access stakeholders on darovasertib.
• Stay current with advancements in methodologies and best practices; monitor new trends in health policy and payer environment and integrate into cross‑functional strategies.
• Influence the design of IDEAYA’s clinical development programs through global price and market access and commercial opportunity assessments.
• Oversee budgeting and financial planning for all HEOR/RWE activities.

• Advanced, doctoral level degree in a related discipline with at least 10‑15 years of related experience.
• Experience in the biotech/pharmaceutical industry in US HEOR/RWE and with market access strategies.
• Experience with rare disease and oral drugs is strongly preferred.
• Demonstrated success with US commercialization and launches.
• Deep technical knowledge and experience with clinical and HEOR/RWE data sets, methodologies, analyses, and processes to optimize execution of value evidence tactics.
• Experience developing US and global value evidence generation plans for pipeline assets.
• Experience establishing relationships with clinical and HEOR experts.
• Experience interacting with US access decision‑makers.
• Excellent communication and presentation skills, ability to present to diverse stakeholders including external partners, healthcare professionals and senior leaders.
• Excellent organizational, project management and problem‑solving skills.
• Ability to thrive in a fast‑evolving environment.
• In‑office role (4x per week) with approximately 15% travel to vendor partners and relevant conferences/meetings as deemed necessary.

• Competitive total rewards package including merit‑based salary increases, discretionary short‑term incentive plan participation, and discretionary stock option awards.
• Medical, dental, and vision coverage (100% company paid for employees and 90% for dependents).
• 401(k) with company match, ESPP, and wellness programs.

All employees are…