Senior Research Associate

Description:

Job Title:

Senior Research Associate

Location:

South San Francisco, CA

Zip Code: 94080

Duration: 7 Months

Pay Rate: $48/hr.

Keyword's: #South San Francisco jobs ; #Research Associate jobs;

Start Date:

Immediate

We provide a competitive pay and benefits package. This position is offering a pay range of $48/hr. however, Belcan considers several factors when extending an offer, including but not limited to education, experience, geographic location, and discipline. Benefits offered may include health care, dental, vision, life insurance; 401(k); education assistance; paid time off including PTO, holidays, and any other paid leave required by law.

DESCRIPTION:

Position Summary

The Senior Research Associate will design, execute, and analyze experiments that support discovery and translational research programs in solid tumor biology and immuno-oncology. The successful candidate will work closely with scientists and cross-functional partners to generate high-quality data using organoid, tumoroid, primary sample, mammalian cell culture, and immune-cell-based assay systems.

This is a laboratory-based role requiring strong technical execution, careful experimental documentation, and the ability to troubleshoot complex biological systems. The ideal candidate is scientifically curious, collaborative, organized, and comfortable working in a fast-paced research environment.

• Culture, maintain, expand, and characterize mammalian cell lines, organoids, tumoroids, and other advanced 2D/3D cellular models.
• Perform molecular, cellular, and immunology-based assays to support oncology and immuno-oncology research programs.
• Design and execute experiments using techniques such as qPCR, ELISA, Western blotting, imaging-based assays, viability/proliferation assays, cytokine assays, and other standard molecular biology and immunoassay workflows.
• Support development and optimization of organoid/tumoroid assays using solid tumor models and, where applicable, patient-derived or primary samples.
• Conduct immune-cell-based functional assays, including T cell activation, T cell killing, TDCC, ADCC, cytokine release, and related immuno-oncology assays.
• Conduct flow cytometry experiments, including sample preparation, staining, acquisition, and analysis, where relevant to program needs.
• Work with primary immune cells and/or tumor samples to evaluate immune-mediated anti-tumor activity.
• Analyze, interpret, and present experimental results to project teams.
• Troubleshoot experimental challenges and contribute ideas for assay improvement.

• Bachelor"s degree in Biomedical Sciences, Immunology, Molecular Biology, Cell Biology, Cancer Biology, or a related discipline.
• Minimum of 1-2 year of research experience in an academic or industry lab.
• Hands-on experience with organoid culture or other advanced 3D cellular model systems.
• Strong experience with mammalian cell culture, including sterile technique, cell maintenance, expansion, banking, and assay preparation.
• Experience with T cell biology and immune-cell-based assay systems.
• Working knowledge of current molecular, cellular, and immunology-based assays.
• Experience with functional immunoassays such as TDCC, ADCC, T cell activation, immune-cell killing assays, cytokine release assays, or related workflows.
• Ability to generate reliable, reproducible data and communicate results clearly.
• Strong organizational skills and attention to detail.
• Ability to work independently while contributing effectively to a collaborative team environment.

• Master"s degree in Biomedical Sciences, Immunology, Molecular Biology, Cell Biology, Cancer Biology, or a related field.
• Experience with flow cytometry, including staining panel execution, data…