Associate Scientist In Vivo Pharmacology, Oncology

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnesses drives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Lets do this. Lets change the world. In this vital role you will work onsite at Amgens South San Francisco campus as part of a fast-paced, integrated, and collaborative in vivo research team exploring therapeutics for oncology programs. You will be responsible for generating and communicating in vivo pharmacology data to support the progression of innovative oncology and immunotherapy research programs.

• Carry out hands-on in vivo work in mice, including handling, tumor inoculation and measurement, dosing (oral, SC, IP, and IV), blood and tissue collection, and health monitoring.
• Perform necropsies and support ex vivo tissue activities, including dissection, processing, sample preparation, and experimental readouts.
• Perform in vitro work including multiparametric flow cytometry and molecular biology techniques associated with in vivo studies.
• Strong communication to support study execution, maintain accurate study records, and present results.
• Active participation and presentation at cross-departmental teams and meetings
• Participate in dosing rotations, including occasional evening or weekend work.

We are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a highly motivated and proactive researcher who wants to contribute to cutting edge science and serve patients with these qualifications.

• Masters degree and 2+ years of experience in in-vivo work with rodents
• Bachelors degree and 4+ years of experience in in-vivo work with rodents
• High school diploma / GED and 6 years of experience in in-vivo work with rodents

• M.S. degree in Oncology, Biology, or related disciplines, or B.S. degree with commensurate scientific / drug discovery experience and track record of scientific excellence and productivity.
• Hands-on experience with in-vivo models of cancer in an academic or industry setting and experience in pharmacology.
• Proficiency in various mouse techniques such as dosing, in vivo PK/PD/Efficacy, health monitoring, blood and tissue collection, preferably for small molecule oncology therapeutics.
• Experience with PDX models of cancer.
• Hands-on experience with in vivo bioluminescence imaging (BLI)
• Flow cytometry and multi-parametric analysis experience is strongly desired.
• Hands-on experience with molecular, cellular, and ex vivo biological techniques and assays
• Computer literacy and proficiency with Graph Pad Prism, Excel, PowerPoint, Word and scientific software.
• Attention to detail, excellent organizational and…