Director - Oncology Research

Career Category Research Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year.

Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based.

If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

Let’s do this. Let’s change the world. Amgen is a leader in the discovery and development of innovative cancer therapeutics. The Oncology Research team seeks a Director of Research to develop and lead a portfolio of antibody-based therapeutics for solid tumors. In this role, you will work cross-functionally to implement and advance next-generation approaches for cancer therapeutics. The ideal candidate will have direct experience leading oncology T-cell engager programs from discovery to development candidate nomination, with experience using translational biology approaches to inform clinical development.

A deep and broad understanding of cancer cell biology, including human genetics, cell growth signaling pathways, mechanisms of response and resistance, and translational pharmacology will be essential. You will be responsible to lead project teams and external collaborations, as well as to inspire and develop a creative, dedicated research team. You will be an exceptional scientific leader who can translate strategy to execution in a fast-paced, changing matrixed environment.

This role has the potential for high visibility within Amgen and externally.

• Lead preclinical research for T cell engager focused on identification of novel target opportunities, prioritization of discovery investments, and implementation of next-generation target discovery approaches.
• Build and lead a portfolio of innovative research programs focused on bispecific antibodies.
• Lead a team of project leaders and lab-based scientists to; create an inclusive high-performing environment that enables new target discovery, rigorous science and efficient execution.
• Lead cross-functional teams and engage key internal partners to integrate tumor biology, target validation, translational research, therapeutic modality considerations, and portfolio strategy.
• Establish productive external scientific collaborations and contribute to evaluation of external opportunities, including business development diligence.
• Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target and biology evaluation.

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

• Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 4 years…