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Director - Oncology Research

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: BioSpace
Full Time position
Listed on 2026-09-25
Job specializations:
  • Research/Development
    Research Scientist, Oncology Care, Medical Science, Clinical Research
Salary/Wage Range or Industry Benchmark: 300000 - 360000 USD Yearly USD 300000.00 360000.00 YEAR
Job Description & How to Apply Below

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnesses drives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director Oncology Research What you will do

Lets do this. Lets change the world. Amgen is a leader in the discovery and development of innovative cancer therapeutics. The Oncology Research team seeks a Director of Research to develop and lead a portfolio of antibody-based therapeutics for solid tumors. In this role, you will work cross-functionally to implement and advance next-generation approaches for cancer therapeutics.

Key Responsibilities
  • Lead preclinical research for T cell engager focused on identification of novel target opportunities, prioritization of discovery investments, and implementation of next-generation target discovery approaches.
  • Build and lead a portfolio of innovative research programs focused on bispecific antibodies.
  • Lead a team of project leaders and lab-based scientists to; create an inclusive high-performing environment that enables new target discovery, rigorous science and efficient execution.
  • Lead cross-functional teams and engage key internal partners to integrate tumor biology, target validation, translational research, therapeutic modality considerations, and portfolio strategy.
  • Establish productive external scientific collaborations and contribute to evaluation of external opportunities, including business development diligence.
  • Partner effectively with peers across research and development to advance new science and integrate technology with tumor cell biology, including application of AI/ML approaches to target and biology evaluation.
What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications

Doctorate degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 4 years of directly related experience

OR

Masters degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 8 years of directly related experience

OR

Bachelors degree in Cancer Biology, Cell Biology, Genetics, or related field [and relevant post-doc where applicable] and 10 years of directly related experience

In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications
  • Doctoral degree in a Cancer Biology, Cell Biology or related field with at least 12 years industry experience following completion of postdoctoral training.
  • Demonstrated experience leading drug discovery and development programs through IND/CTA-enabling activities, with strong experience in large-molecule therapeutics and understanding of the preclinical data sets required for development candidate nomination.
  • Deep understanding of oncology and tumor biology; expertise in NSCLC or lung cancer biology is strongly preferred.
  • Knowledge of antibody engineering approaches, with direct experience designing and evaluating modalities including T-cell engagers and antibody-drug conjugates.
  • Established record of building, mentoring, and leading high-performing research teams.
  • Exceptional written and verbal communication skills, with the ability to synthesize complex data into…
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