Director, Clinical Trial Finance

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top‑tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location.

Reporting directly or operationally into the Executive Director, FP&A, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration

The Director, Clinical Trial Finance will lead financial planning and oversight of clinical trial activities, including accruals, in support of the company’s development portfolio. Reporting to the Executive Director, FP&A, this role serves as a key strategic partner to Clinical Operations, Development, FP&A, and Accounting, ensuring strong financial governance, accurate reporting, and actionable insights to inform decision‑making.

The ideal candidate brings deep expertise in biotech finance, a thorough understanding of clinical development, and a strategic, hands‑on approach to driving financial performance in a dynamic, growth‑oriented environment.

This is an opportunity to play a critical role in advancing a global, publicly traded biotech company’s pipeline and supporting the successful execution of clinical programs.

• Drive financial planning, budgeting, forecasting, and long‑range planning for clinical trials; oversee financial management across programs, including accruals and variance analysis, in alignment with corporate objectives.
• Oversee financial management of clinical trial contracts, amendments, and compliance with financial terms.
• Partner closely with Accounting to ensure accurate and timely financial close processes, including journal entries, reconciliations, and reporting of clinical trial costs.
• Serve as the primary finance business partner to Clinical Operations, Development, and Program Management, providing insights and ad hoc financial reporting to support decision‑making.
• Establish and maintain strong relationships with Contract Research Organizations (CROs), vendors, and external partners.
• Collaborate across Clinical organization to define key financial drivers, timelines and milestones for clinical trials.
• Lead audit readiness efforts and support internal and external audits related to clinical trial expenditures.
• Continuously enhance financial processes, systems, and internal controls to support scalability and operational excellence.

Experience

• 10+ years of finance experience, including 7+ years in increasingly responsible roles within finance and accounting, with significant experience supporting clinical trials in the biotech or pharmaceutical industry.
• Deep industry experience with strong understanding of clinical development, industry dynamics, and key financial drivers.
• Strong knowledge of GAAP and SOX compliance, with deep expertise in accrual accounting and clinical trial financial management,…