Senior Principal Scientist - Medicinal Chemistry

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this. Let’s change the world.

Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in South San Francisco CA (ASF) where we are building brand new state-of-the art chemistry labs.

This Senior Principal Scientist role will be part of an innovative Medicinal Chemistry group, with primary responsibilities being the design of novel compounds for potential clinical development, while also serving as a Project Team Representative (PTR).

In addition, this Senior Principal Scientist role will help recruit top talent and lead several PhD level chemists in the design and synthesis of potential drug candidates.

As a manager of others, this role will be responsible for providing motivating professional development guidance and/or coaching of colleagues within their group.

As a PTR, this role will typically also manage an external synthetic chemistry team and work together with a diverse cross-functional team of research scientists to help determine team direction and advance programs in Amgen’s small molecule portfolio. Additional responsibilities include but are not limited to regularly communicate progress and strategy in various forums.

Expectations for this role are to be full time onsite at our Research and Development facility in South San Francisco CA (ASF).

We are all different, yet we all use our unique contributions to serve patients. The qualified professional we seek is a Senior Principal Scientist with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR Pharm

D OR MD [and relevant post-doc where applicable] and 2 years of medicinal chemistry experience or

Master’s degree and 5 years of medicinal chemistry experience or

Bachelor’s degree and 7 years of medicinal chemistry experience

Preferred Qualifications:

• Doctorate degree in chemistry specializing in organic chemistry and 8+ years of experience in synthetic organic and medicinal chemistry
• Experience participating on or leading medicinal chemistry teams to deliver candidates for clinical development
• Track record of successful drug discovery accomplishments (e.g. patent inventorship, conference presentations, and peer-reviewed publications)
• Proven understanding of relevant drug discovery disciplines (e.g. chemistry, biology, safety, PKDM, etc.)
• Expert in modern medicinal and synthetic chemistry approaches
• Demonstrated experience managing several direct reports
• Excellent collaboration and communication skills (both written and oral)

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and…