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Executive Director, Research Oncology

Job in South San Francisco, San Mateo County, California, 94080, USA
Listing for: Amgen
Full Time position
Listed on 2026-08-05
Job specializations:
  • Science
    Oncology Care
Job Description & How to Apply Below

Executive Director, Oncology Research

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What You Will Do

Let's do this. Let's change the world. In this vital role as the Executive Director, Oncology research you will drive the discovery and development of novel therapeutics for solid tumors and hematologic malignancies. This is a high-visibility role offering the opportunity to shape strategy, lead cutting-edge science, inspire talent, and deliver meaningful impact for patients worldwide. Our Oncology Research team is at the forefront of this effort, advancing a bold pipeline of next-generation medicines.

The Executive Director will have extensive experience in oncology drug development, including proficiency leading large molecule and small molecule project teams from target discovery and validation to clinical candidate selection, and supporting clinical and translational studies. The Executive Director will have deep and broad knowledge of cancer biology, including cell signaling pathways, tumor genetics and subtypes, and mechanisms of response and resistance to existing therapeutics, will be essential.

The ability to integrate large-scale human datasets, AI/ML, and translational insights into the research portfolio will be an advantage.

The Executive Director will have a central role in co-creating the next generation of antibody-drug conjugate (ADC) therapeutics. You will lead a research team, be responsible for a portfolio of preclinical programs, and drive preclinical activities to support clinical programs and external collaborations. You are a scientific leader who inspires your team and develops talent at all levels. Your strategic vision and scientific expertise will be balanced by flexibility, resilience, and a demonstrated ability to excel in a fast-paced, matrixed environment.

Responsibilities

  • Drive research strategy and execution for a differentiated oncology portfolio. This effort will initially focus on ADCs and is expected to expand into other modalities.
  • Lead and develop high-performing teams of project leaders and scientists, fostering a culture of innovation, accountability, and growth.
  • Advance preclinical programs and partner cross-functionally with clinical development and biomarker teams to translate insights into next-generation therapies.
  • Leverage data and technology to accelerate discovery and decision-making.
  • Shape external collaborations, including academic partnerships and business development opportunities.

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.

  • Doctorate degree & 6 years of oncology research experience OR
  • Master's degree & 10 years of oncology research experience OR
  • Bachelor's degree & 12 years of oncology research experience AND
  • 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications:

  • Doctorate degree (PhD) in Cancer Biology, Cell Biology, or a related discipline with at least…
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