Sr AI Fullstack Engineer; GC​/Citizens, W2

Sr AI Fullstack Engineer (GC/Citizens, W2 Only)

South San Francisco, United States | Posted on 01/21/2026

Our client, a world leader in biotechnology and life sciences, is looking for a"Sr AIFullstack Engineer” based out of South San Francisco, CA.

Job Duration:

Long Term Contract(Possibility Of Extension)

Pay Rate : $85/hr on W2

DOE

Company Benefits:
Medical, Dental,Vision, Paid Sick leave, 401K

Duration:
Long term contract (Possibility of further extension)

The Sr AI Fullstack Engineer will primarily be responsible for designing, developing, and deploying software which interacts with cutting-edge generative AI models and applications in collaboration with AI scientists, full stack developers, andothers.

• Innovate and develop software applications to support clinical development
• Identify and integrate
  
  AI/LLM capabilities to enhance data processing and natural workflows.
• Design intuitive,user-centric interfaces.
• Code Quality and Documentation:
  Write clean, maintainable, and well-documented code. Participate in code reviews and contribute to best practices in software development.
• Research and Innovation:
  Stay up-to-date with the latest advancements in generative AI and machine learning. Evaluate new technologies and methodologies to continuously improve our solutions.
• Collaborate with Cross-Functional Teams:
  Work closely with data scientists, engineers, and product managers to integrate generative AI capabilities into our products and services.
• Deployment and Monitoring:
  Develop and maintain robust deployment pipelines for AI-enhanced applications. Monitor pipeline performance in production and implement necessary improvements.

• Bachelor’s or Master’sdegree in Computer Science, Engineering, Mathematics, or a related field.
• 5+ years of full stack development experience
• 4+ years experience with front-end frameworks (preferably Vue.js)
• 2+ years of developing and deploying AI/ML solutions or applications
• Experience designing and developing RESTful APIs (with e.g. Python FastAPI).
• Familiarity with promptengineering
• Proficiency with containerized workflows and architectures (Podman, Docker, Kubernetes)
• Strong automated software testing skills (Python unittest, jest, Playwright)
• Familiar with Agile methodologies
• Leading system designand implementing scalable, fault-tolerant solutions for complex, distributed computing challenges.
• Experience with cloud platforms (e.g. AWS) and modern data platforms (e.g., Snowflake).
• Experience implementingchatbots, retrieval-augmented generation (RAG) systems, and integrating LLMsinto applications (AI-assisted automation)

• Experience building AIagents, fine-tuning LLM models, and evaluating bias and fairness with LLMsystems
• Experience in developing Microsoft Word add-ins using Office.js.
• Experience with web technologies like JWT, Web Sockets, etc.
• Experience with Huggingface, Langchain, Tensor Flow, PyTorch, or similar.
• Familiarity with
  
  DevOps, infrastructure, and continuous integration concepts.
• Familiarity with CRDTtechnologies like Yjs.
• Experience with using
  
  NLP/LLMs on clinical text.
• Basic knowledge of clinical drug development