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Director​/Senior Director, Software Engineering

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Genentech, Inc
Full Time position
Listed on 2026-06-01
Job specializations:
  • Software Development
    AI Engineer (Applied/Software), Software Engineer, Data Engineering, Machine Learning/ ML Engineer
Salary/Wage Range or Industry Benchmark: 150000 - 200000 USD Yearly USD 150000.00 200000.00 YEAR
Job Description & How to Apply Below

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

Within the CoE organisation, the Data and Digital Catalyst (DDC) organisation drives the modernisation of our computational and data ecosystems and integration of digital technologies across Research and Early Development to enable our stakeholders, power data-driven science and accelerate decision‑making.

One of the Engineering Capability teams in the DDC Organization is called Solutions. The solutions team is building a modernised and interconnected computational and data ecosystem. On top of the Data Ecosystem we are building engineering solutions to accelerate the work done by our Computational and Bench Scientists and enable the work done on ML/AI. Our team specialises in building Data Pipelines and Applications for data acquisition, collection, storage, transformation, linkage and sharing.

Join our team, where you will shape the future of our data solutions. In this pivotal role, you will lead a talented team of engineers to design and deliver innovative engineering solutions that impact stakeholders across our global organisation, from lab scientists to AI specialists. Your vision and leadership will be crucial in building collaborative partnerships and fostering an engaging team culture built on trust and impact.

The

Opportunity

In this position, you will make a significant impact by:

  • Driving an AI‑first transformation and connecting cutting‑edge artificial intelligence with enterprise software engineering, guiding the organisation from traditional development towards an AI‑native approach in both the products we build and the tools we use to build them.
  • Combining rigorous, hands‑on technical depth with a sharp understanding of the competitive landscape to build and deliver software systems leveraging the best available AI techniques and tools.
  • Providing strategic engineering leadership, identifying new opportunities to build common, scalable solutions.
  • Leading, mentoring, and developing a diverse team of software, data, and machine learning engineers, fostering a culture of growth and collaboration.
  • Driving the technical vision and delivery of robust data flows and applications across key domains like Research and Development.
  • Overseeing the full talent lifecycle, from implementing an inclusive recruitment strategy to retaining and developing your team members.
  • Championing technical excellence by improving our application architecture and data ecosystem, leveraging modern, cloud‑first, and API‑first patterns.
  • Making key technical decisions to reduce technical debt and drive the consolidation of legacy systems.
  • Enabling advanced analytics and AI/ML capabilities by delivering integrated data sets and facilitating model implementation.
  • Building and maintaining strong partnerships with key stakeholders and leaders across our global organisation.
Who You Are

We are looking for a leader who is passionate about technology, people, and creating impactful solutions. You can think strategically while delivering on commitments, and you thrive in a collaborative environment. You deliver your commitments while leveraging the best in class AI tools and processes.

To be successful in this role, you should have:

  • Bachelor’s…
Position Requirements
10+ Years work experience
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