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Associate Director, Scientific Computing and AI Engineer

Job in South San Francisco, San Mateo County, California, 94083, USA
Listing for: Scorpion Therapeutics
Full Time position
Listed on 2026-07-08
Job specializations:
  • Software Development
    AI Engineer (Applied/Software), Machine Learning/ ML Engineer, Data Engineering
Salary/Wage Range or Industry Benchmark: 159000 - 207000 USD Yearly USD 159000.00 207000.00 YEAR
Job Description & How to Apply Below

Scientific Computing & HPC Platform Engineering

  • Lead architecture, build-out, and optimization of on-premise GPU clusters, hybrid cloud HPC environments, and supporting storage/network infrastructure
  • Partner with research scientists to profile workloads, size infrastructure, and iteratively improve job performance and self-service
  • Design, operate, and support compute environments for computational workloads (e.g., molecular dynamics, CryoEM, genomics, structural biology, AI model training)
  • Implement scheduler configurations (Slurm/LSF), parallel file systems, and interconnect optimization to maximize throughput/utilization
  • Architect cloud-burst strategies for elastic scaling of peak HPC/ML training demand
Applied AI Engineering & Generative AI Solutions
  • Design/engineer production AI/ML and generative AI systems (cloud infrastructure, data pipelines, vector databases, RAG, LLM application layers)
  • Build/deploy agentic AI workflows to automate/augment scientific processes
  • Develop AI evaluation frameworks, prompt engineering standards, and MLOps for reliable, auditable outputs in a GxP-adjacent environment
  • Prototype/pilot AI capabilities (AI agents, digital twins, foundation model fine-tuning) and transition to production
  • Scope AI use cases, define success criteria, and demonstrate value via proofs of concept and deployments
  • Implement Infrastructure as Code and CI/CD with integrated security/compliance controls
Technical Leadership & Architecture Guidance
  • Set engineering standards, reference architectures, and technology guardrails; mentor engineers
  • Translate technical concepts for non-technical stakeholders
  • Evaluate technologies; lead proof-of-concept assessments and build‑vs‑buy decisions
  • Participate in architecture reviews for platform coherence
Requirements
  • Bachelor’s/Master’s in CS, Engineering, or related field
  • Typically 10–12+ years experience; 3+ years at senior/principal IC level
  • Deep expertise in 2+ areas: HPC (Slurm/LSF, parallel file systems, GPU/CUDA), cloud production platform engineering, AI/ML platform engineering (model deployment, MLOps, LLM apps), generative/agentic systems (Lang Chain, Lang Graph, Auto Gen, foundation models)
  • Infrastructure as Code and CI/CD proficiency; strong Python/scripting
  • Experience in regulated biotech/pharma/life sciences with GxP or 21 CFR Part 11/data integrity
  • Hands‑on vector databases/knowledge graphs and RAG architectures
Compensation & Benefits

Salary range: $159,000–$207,000; 401k, healthcare coverage, ESPP, and other benefits

Learn more:

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Position Requirements
10+ Years work experience
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