Medical Science Liaison-Northeast

## Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
** Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
**** Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.
**** Medical Science Liaison, Endocrinology
** The Medical Science Liaison, Endocrinology (MSL) is a field-based medical role focused on building and maintaining scientific partnerships with healthcare professionals (HCPs) and key decision-makers through non-promotional, evidence-based scientific exchange. The MSL will serve as a key liaison for Madrigal’s clinical and scientific efforts in MASH/NASH, engaging thought leaders (TLs), academic centers, community practices, and regional organizations to support disease education, clinical research, and launch readiness.
** Key Responsibilities
*** Establish Madrigal’s presence and scientific leadership in MASH/NASH and chronic liver disease.
* Identify, develop, and maintain long-term collaborations with TLs, clinical investigators, and key stakeholders within the assigned geography.
* Deliver peer-to-peer, scientifically balanced exchanges on MASH/NASH disease state and Madrigal’s clinical programs and investigational therapies.
* Serve as a scientific expert to internal stakeholders, contributing to launch planning, field-based insights, and development of medical communication strategies.
* Provide scientific and strategic input for investigator-initiated trials, research collaborations, and site support in partnership with Clinical Development.
* Facilitate internal scientific training and contribute to speaker programs, advisory boards, and other medical affairs activities.
* Represent Madrigal at national and regional scientific and medical conferences, supporting booth activities and engaging with HCPs to capture real-world insights.
* Respond compliantly to unsolicited medical information requests, ensuring documentation aligns with internal processes and regulatory standards.
* Maintain strict compliance with applicable laws, industry codes, and company policies, with a strong grasp of US healthcare and regulatory environments.
** Qualifications
* ** Advanced degree in a scientific or healthcare discipline (e.g., MD, DO, Pharm

D, PhD, DNP, PA-C).
* Minimum 3 years of previous MSL experience in a pharmaceutical or biotech industry, preferably in a field-based medical role.  Prior experience in Endocrinology preferred.  Postdoctoral, academic, or government experience may be considered.
* Solid knowledge of clinical medicine, disease management, and medical research, ideally within hepatology or gastroenterology.
* Strong understanding of the US healthcare system, care delivery, and payer environment.
* Familiarity with FDA regulations, ICH/GCP guidelines, and legal considerations relevant to medical affairs and research.
* Proven ability to synthesize and communicate complex scientific data clearly and concisely to diverse audiences.
* Excellent project management, collaboration, and communication skills.
* Highly motivated and adaptable team player with the ability to work cross-functionally across commercial, clinical, and access teams.
* Proficient in digital tools including CRM platforms, Microsoft Office Suite, and virtual collaboration…