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Associate Scientist RNA Oligonucleotide Chemistry

Job in Springfield, Hampden County, Massachusetts, 01119, USA
Listing for: 6AM City, LLC
Full Time position
Listed on 2026-06-18
Job specializations:
  • Research/Development
    Research Scientist
  • Science
    Research Scientist
Salary/Wage Range or Industry Benchmark: 80000 - 100000 USD Yearly USD 80000.00 100000.00 YEAR
Job Description & How to Apply Below

Job Description

Our Client is seeking an individual to work closely with the RNA Chemistry Team responsible for synthetic oligonucleotides. This individual will be involved in a complete production process for the identification, implementation & fulfillment of synthesis, purification and reaction scheme analytical characterization and method development of oligonucleotides.

RESPONSIBILITIES
  • Hands‑on position in an oligonucleotide chemistry lab inclusive of operating, maintaining & calibrating synthesis platforms and other scientific equipment.
  • Handling automated oligo synthesizer (Expedite, Dr.Oligo, Mermaid, Akta OP-100, etc) using solid‑phase.
  • Knowledge of oligonucleotide purification techniques (using Akta system) and Unicorn software.
  • Synthetic oligonucleotide method and process development participation.
  • Demonstrate basic lab competency in preparing reagents and buffers & handling chemicals.
  • Follow operating procedures and process improvement documents.
  • Documentation of results and data analysis.
  • Ensure safety and product quality are paramount throughout the laboratory environment.
  • Capable of repetitive tasks and performing other duties as assigned.
  • Perform general lab‑operation activities.
QUALIFICATIONS
  • B.S. or B.A. equivalent in Organic Chemistry, Biochemistry or related field with 10+ yrs general laboratory experience or M.S. in Organic Chemistry, Biochemistry or related field and 5+ yrs laboratory experience.
  • Basic computer skills including MS Office Suite.
  • More experienced candidates with oligonucleotide chemistry experience will be strongly considered.
EEO Statement

Beacon Hill is an Equal Opportunity Employer that values the strength diversity brings to the workplace. Individuals with Disabilities and Protected Veterans are encouraged to apply. If you would like to complete our voluntary self‑identification form, please visit  Completion of this form is voluntary and will not affect your opportunity for employment, or the terms or conditions of your employment. This form will be used for reporting purposes only and will be kept separate from all other records.

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Position Requirements
10+ Years work experience
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