Manager, Accounting

About Beeline Medicines

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category‑leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best‑in‑class and first‑in‑disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life‑changing impact.

Led by an established executive team and backed by world‑class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune‑mediated diseases can live life fully.

The Manager, Accounting is a highly experienced, strong individual contributor responsible for executing and owning complex accounting operations across the organization's general ledger, financial close process, and reporting functions. This individual is expected to bring deep accounting expertise, independent judgment, and a high degree of self‑direction to all responsibilities without the need for direct report oversight. This person serves as a senior accounting resource and operational backbone of the Finance team, partnering closely with the VP, Accounting & Controlling to execute tasks in all areas of the day to day accounting and the month end close to ensure the accuracy, integrity, and timeliness of all financial records in compliance with US GAAP and the organization's internal control standards.

The ideal candidate is a seasoned accountant who has seen a wide variety of accounting scenarios, operates with minimal supervision, and takes full ownership of their functional areas.

Hybrid – This position follows a hybrid work schedule, requiring a minimum of two (2) days on‑site per week – currently designated as Tuesday and Wednesday
. Additional on‑site days may be required based on business needs, team priorities, or leadership direction.

• Own and execute the end‑to‑end monthly, quarterly, and annual financial close process – managing the general ledger, preparing and reviewing journal entries, performing account reconciliations, and ensuring the timely and accurate close of all assigned accounting areas.
• Prepare and maintain complex accounting schedules and analyses across areas including prepaid expenses, accruals, fixed assets, lease accounting (ASC 842), and clinical and research program cost tracking – applying independent technical judgment to ensure accurate financial representation.
• Support the preparation of financial statements, management reporting packages, and board‑level financial materials – ensuring all outputs are accurate, complete, and presented with appropriate context and supporting detail.
• Own the organization’s accounts payable and vendor payment process – reviewing and approving invoices, maintaining vendor records, ensuring proper coding and approval workflows, and driving process efficiency and compliance.
• Serve as the primary point of contact for external audit support – preparing audit schedules, responding to auditor inquiries, coordinating document requests, and proactively maintaining audit‑ready work papers throughout the year.
• Identify, recommend, and implement improvements to accounting processes, internal controls, and financial systems – bringing a continuous improvement mindset to all operational accounting activities and proactively flagging risk areas to the VP, Accounting & Controlling.
• Perform other duties and responsibilities as assigned.

• Education:
  
  Bachelor's degree in accounting, finance, or a related discipline required; CPA designation strongly preferred and may be required.
• Minimum of 3 years of progressive accounting experience, with demonstrated depth across general ledger, financial close, technical accounting, and external audit support.
• Strong knowledge of US GAAP and Public accounting experience (Big 4 or national firm) combined…