Director, Accounting Area

Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category‑leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best‑in‑class and first‑in‑disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life‑changing impact.

Led by an established executive team and backed by world‑class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune‑mediated diseases can live life fully.

The Director, Accounting is responsible for leading the company's accounting operations, financial reporting, and internal controls framework, ensuring the accuracy, integrity, and compliance of all financial information in accordance with US GAAP and applicable regulatory standards. This role serves as a senior financial leader within a pre‑commercial I&I biotechnology company, overseeing general ledger management, month‑end and quarter‑end close processes, financial statement preparation, and external audit coordination.

The Director partners closely with Finance, Legal, Procurement, and external advisors to build a scalable, audit‑ready accounting infrastructure that supports the company's clinical programs, investor reporting obligations, and long‑term path to commercialization.

Hybrid:
This position follows a hybrid work schedule, requiring a minimum of two (2) days on‑site per week – currently designated Tuesday and Wednesday. Additional on‑site days may be required based on business needs, team priorities, or leadership direction.

• Lead all core accounting operations, including general ledger management, accounts payable, accounts receivable, payroll accounting, and fixed asset management, ensuring accuracy, completeness, and timeliness of all financial records.
• Own the monthly, quarterly, and annual financial close processes, including journal entry review, account reconciliations, accrual management, and preparation of GAAP‑compliant financial statements.
• Develop, implement, and continuously improve the company's internal controls framework, ensuring compliance with US GAAP, Sarbanes‑Oxley (SOX) principles where applicable, and company financial policies.
• Manage the external audit relationship, serving as the primary point of contact for auditors and overseeing the preparation of all audit schedules, supporting documentation, and financial disclosures.
• Oversee the accounting treatment for complex or technical transactions, including clinical trial accruals, equity‑based compensation (ASC 718), lease accounting (ASC 842), and research and development expenditure classification.
• Partner with Financial Planning & Analysis (FP&A) and Procurement to ensure alignment between budget forecasts, purchase orders, vendor accruals, and actual expenditures, with particular focus on clinical and CMC program spend.
• Lead the development and implementation of accounting policies, standard operating procedures, and a chart of accounts appropriate to a growing clinical‑stage biotechnology company.
• Manage the accounting systems ecosystem, including the ERP platform, expense management tools, and financial reporting software; lead system implementations or upgrades as required.
• Oversee federal, state, and local tax compliance activities in coordination with external tax advisors, including corporate income tax, sales and use tax, and R&D tax credit programs.
• Build, lead, and develop the Accounting team, providing mentorship, performance management, and professional development support to ensure high‑quality execution and succession depth within the function.
• Perform other duties and responsibilities as assigned.

• Education:
  
  Bachelor's degree in accounting, finance, or a related discipline required; CPA designation strongly…