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Nurse Practitioner​/Physician Assistant - Early Therapeutics

Job in Tampa, Hillsborough County, Florida, 33602, USA
Listing for: Moffitt Cancer Center
Full Time position
Listed on 2026-04-21
Job specializations:
  • Nursing
    Nurse Practitioner, Oncology Nurse, Advanced Practice Nurse/APRN, Clinical Research Nurse
Job Description & How to Apply Below
Position: Nurse Practitioner / Physician Assistant - Early Therapeutics
Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer.

As the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, Moffitt employs some of the best and brightest minds from around the world. Join a dedicated team of nearly 10,000 who are shaping the future we envision.

Moffitt has been recognized as a Best and Brightest Company to Work for in the Nation, a Digital Health Most Wired Organization and continually named one of the Tampa Bay Time's Top Workplaces.

A National Cancer Institute (NCI)-designated Comprehensive Cancer Center since 2001.

Summary

Nurse Practitioner / Physician Assistant - Early Therapeutics

Position Highlights:

* Assists physicians and principal investigators with the evaluation, management, and treatment of a broad spectrum of patients participating in early-phase clinical trials, primarily in solid tumor oncology, with exposure to diverse therapeutic modalities (e.g., targeted therapies, immunotherapies, cellular therapies, etc.)

* Works within a defined scope of practice and under the authority of supervising physician(s), study investigators, and/or specific clinical trial protocols.

* Plays a key role in the delivery of cutting-edge investigational therapies within a dedicated Clinical Research Unit, ensuring patient safety, protocol compliance, and high-quality clinical care.

* Engages in a highly collaborative, academic environment with opportunities to contribute to innovative cancer research and advancement of new therapeutics.

Responsibilities:

* Provides comprehensive patient care as a member of an interdisciplinary clinical and research team, collaborating closely with oncologists, research nurses, pharmacists, and other specialists to coordinate and optimize care for patients enrolled in clinical trials.

* Performs detailed clinical assessments, including history and physical examinations, with an emphasis on identifying eligibility, toxicity, and response in accordance with study protocols.

* Correlates subjective and objective data to formulate differential or working diagnoses, particularly in the context of complex oncology patients and investigational treatments.

* Formulates and implements treatment and management plans for medical conditions and treatment-related toxicities within scope of practice and protocol requirements.

* Monitors and manages adverse events, including immune-related and novel therapy-associated toxicities, ensuring timely reporting and adherence to regulatory and protocol guidelines.

* May perform minor procedures within scope of practice, as required for patient care and protocol-specific assessments.

* Prescribes oral and intravenous medications, including supportive care therapies and protocol-directed treatments, within scope of practice.

* Ensures accurate, timely, and protocol-compliant documentation of patient care, adverse events, and clinical outcomes in the medical record and research systems.

* Participates in patient education regarding clinical trial participation, investigational therapies, potential risks, and expected outcomes.

* Supports screening, enrollment, and retention of patients in clinical trials, contributing to the successful execution of early-phase research studies.

Credentials and

Qualifications:

* Bachelor's degree at minimum;
Master's or Doctorate degree preferred.

* Graduate of an accredited Advanced Registered Nurse Practitioner (APRN) or Physician Assistant (PA) program.

* Active ACLS and BLS certification required.

* Prior experience in oncology, clinical research, critical care, and/or internal medicine strongly preferred.

* Experience with early-phase (Phase I/II) clinical trials or investigational therapeutics is highly desirable.

* Demonstrated ability to work in a fast-paced, highly collaborative, and protocol-driven environment with strong attention to detail and patient safety.

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