Research Associate II

Working at Moffitt is both a career and a mission: to contribute to the prevention and cure of cancer. As the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, Moffitt employs some of the best and brightest minds from around the world. Join a dedicated team of nearly 11,000 who are shaping the future we envision. Moffitt has been recognized as a Best and Brightest Company to Work For in the Nation and is continually named one of the Tampa Bay Times' Top Workplaces.

The George Laboratory at H. Lee Moffitt Cancer Center in Tampa, Florida, is recruiting a highly motivated Research Associate II to join our translational research team. Our laboratory focuses on developing new therapeutic strategies for ovarian and endometrial cancer, with an emphasis on patient-derived experimental models, targeted therapeutics, treatment resistance, and precision oncology. A major focus of the laboratory is the development and application of patient-derived three-dimensional microtumor models that preserve key features of the tumor microenvironment and can be used for therapeutic testing and translational research.

The Research Associate will work closely with members of the George Laboratory and will be integrated with the Bio Engineering team at Speros, providing an opportunity to work at the interface of cancer biology, engineering, and translational therapeutics.

• Work with fresh patient-derived ovarian and gynecologic tumor specimens and three-dimensional microtumor cultures.
• Perform drug-treatment experiments using patient-derived models and established cancer cell lines.
• Assist with molecular, cellular, and imaging-based assays to evaluate tumor biology and treatment response.
• Work as part of a collaborative team that includes cancer biologists, bioengineers, physicians, and other research staff.
• Gain experience in translational cancer research focused on developing and testing new therapeutic strategies.

• Has experience with mammalian cell culture.
• Experience with primary cells, patient-derived tissues, spheroids, organoids, or other three-dimensional culture systems is preferred but not required.
• Demonstrates proficiency in basic molecular and cellular biology techniques, such as protein extraction, western blotting, immunofluorescence, microscopy, viability assays, and/or flow cytometry.
• Is comfortable learning new laboratory techniques and following established experimental protocols.
• Has strong organizational skills and careful attention to detail.
• Maintains accurate and complete experimental records.
• Is dependable and able to manage time and multiple laboratory tasks efficiently.
• Works well as part of a collaborative research team.

• Process fresh patient tumor specimens according to established laboratory protocols.
• Establish, culture, maintain, and treat patient-derived microtumors and mammalian cell lines.
• Perform routine drug-treatment and cell viability experiments.
• Perform molecular, cellular, and imaging-based laboratory assays according to established protocols.
• Collect, organize, analyze, and document experimental data under the guidance of the principal investigator and research team.
• Maintain accurate laboratory records in physical and electronic formats.
• Maintain laboratory equipment in clean, working order, and assist with routine instrument maintenance and standardization.
• Monitor laboratory supplies and reorder commonly used reagents and materials as needed.
• Assist with the preparation of experimental materials and data for laboratory meetings, presentations, manuscripts, and other research activities as directed.
• Work closely with members of the George Laboratory, Bio Engineering team, and collaborating research groups.

• Bachelor’s degree in biology, biomedical sciences, bioengineering, molecular biology, or a related field is required.
• Master’s degree in a relevant field is preferred.
• Hands-on laboratory research experience is required.
• Experience with mammalian cell culture is strongly preferred.
• Experience with primary human tissues, three-dimensional culture systems, or cancer research is preferred but not required.
• Excellent verbal and written communication skills are required.
• Ability to work both independently and collaboratively within a research team.

• Eligible for an annual Team Member Incentive.
• Eligible for an annual Team Member Merit Increase.
• Eligible for a comprehensive benefits package, including health, financial, and lifestyle coverage.

Salary Range $45,032.00 - $68,744.00 Salary ranges posted for this position represent the expected base pay range for the role. Actual compensation may vary based on location and a variety of job-related factors, including experience, skills, education, and internal equity among Team Members in similar positions. We are committed to maintaining fair and equitable pay practices and regularly review compensation to ensure alignment across our…