Senior Principal Scientist - Bioanalytical Sciences

Regeneron's Assay Development Group (ADG) in Bioanalytical Sciences, located in Tarrytown, NY, is seeking a Senior Principal Scientist. In this exciting role, you will create and execute novel assay strategies for all biotherapeutic modalities, designing experiments, troubleshooting problems, organizing and interpreting experimental results and performing follow-up experiments.

A Typical Day in the Role Might Look Like:

* Develop bioanalytical assay approaches for pharmacokinetic, biomarker assays and immunogenicity assays for a diverse pipeline of novel biotherapeutics, including monoclonal antibodies, bispecifics, antibody-drug conjugates (ADC), adeno-associated virus (AAV), CAR-T, RNA as well as drug target biomarkers to support non-clinical and clinical studies.

* Supervise a team of scientists in the development and validation of immunoassays for the measurement of drug, drug complexes and anti‑drug antibodies to support new programs.

* Guides the designs and execution of immunoassays (PK, PD and ADA) by direct reports, based on protocols provided by literature, seminars and other scientists. Suggests troubleshooting experiments for assay-related problems follow-up experiments to further assay development and optimize assays.

* Routinely reviews data for multiple developmental projects, working on these projects simultaneously.

* Summarizes and presents results internally to management and externally in industry meetings.

* Writes/reviews assay validation protocols, reports and SOPs prior to submission to Quality Auditing (QA). Functions as Study Director for assay validation studies conducted by direct reports.

This Role Might Be For You If You:

* Stimulates, develops, and promotes the scientific and career development of direct and indirect reports.

* Can act as a leader within the group that effectively drives projects forward to meet aggressive timelines

* Can communicate effectively with supervisor, upper management/senior leaders and other members within the company and/or outside vendors to obtain assay-related reagents or discuss reagents needs.

* Propose innovative solutions and troubleshooting to address scientific complexity and challenges.

To be considered for this opportunity, you must have a PhD degree with 5+ or a MS with 8+ or a BS with 10+ years meaningful experience. An in-depth understanding of the science and technology on the development and validation of immunoassays is required. The ability to perform sophisticated technical tasks to pursue projects that incorporate a diverse set of skills and work on multiple projects/experiments simultaneously is helpful.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health…