Senior Research Associate, Molecular Biology

Sarmal, Inc.

Sarmal, Inc. is a San Diego–based biotechnology company developing next-generation genomics and molecular detection platforms. Our work integrates molecular biology, chemistry, and advanced systems engineering to enable faster, more precise, and more accessible genomic insights.

We are a highly collaborative R&D-driven team operating in a fast-paced, early-stage environment. Our scientists and engineers work across disciplines to solve complex technical challenges and translate innovation into scalable, real-world applications.

At Sarmal, we value scientific rigor, curiosity, and a builder mindset. We are looking for individuals who are energized by ambiguity, motivated by impact, and excited to help bring breakthrough technologies from concept to reality.

• Design, execute, and optimize molecular biology experiments with minimal supervision.
• Perform qPCR assays, including assay design, optimization, standard curve generation, and efficiency analysis.
• Carry out nucleic acid extraction from diverse biological matrices using manual and kit‑based methods.
• Execute DNA and RNA quantification using spectrophotometric and fluorometric methods (e.g., Nano Drop, Qubit).
• Generate high‑quality, reproducible data to support research, development, and detection‑focused workflows.
• Prepare, optimize, and maintain buffers, reagents, and working solutions, with attention to stability, compatibility, and performance.
• Perform reagent performance comparisons, including shelf‑life and stress testing.
• Document reagent and buffer formulations, preparation methods, and defined QC acceptance criteria.
• Ensure consistent reagent quality and performance across experiments and studies.
• Handle biological samples (e.g., blood, bodily fluids, tissues) following best laboratory practices.
• Maintain sample integrity through proper storage, labeling, tracking, and documentation.
• Analyze experimental data using appropriate software tools and basic statistical methods.
• Maintain detailed, accurate, and compliant documentation, including lab notebooks, protocols, and technical reports.
• Summarize experimental findings clearly for internal stakeholders and cross‑functional teams.
• Contribute to SOP development, protocol updates, and supporting technical documentation.
• Maintain laboratory organization, equipment readiness, and inventory awareness.
• Follow established quality practices (GLP‑like rigor where applicable).
• Proactively troubleshoot equipment, assay, or process‑related issues.
• Identify opportunities to improve experimental workflows, consistency, efficiency, or data quality.
• Collaborate with scientists, engineers, and operations teams to advance project goals.
• Contribute practical, data‑driven insights to experimental planning and technical decision‑making.

A Research Associate to Senior Research Associate in Molecular Biology is an experienced, hands‑on scientist who independently executes and optimizes molecular assays, supports detection‑focused research through rigorous experimentation and reagent development, and contributes technical expertise to cross‑functional teams with minimal supervision.

• Strong hands‑on expertise in molecular biology techniques, with demonstrated proficiency in qPCR assay development, optimization, and troubleshooting.
• Proven ability to evaluate primer/probe performance, amplification efficiency, inhibition, sensitivity, and assay robustness.
• Solid experience in nucleic acid extraction from diverse biological sample types, with awareness of pre‑analytical variables affecting detection outcomes.
• Proficiency in DNA/RNA quantification using spectrophotometric and fluorometric methods, including interpretation of purity and quality metrics.
• Demonstrated experience in buffer, reagent, and solution preparation, formulation optimization, and performance consistency testing.
• Ability to independently troubleshoot complex experimental challenges and apply data‑driven solutions.
• Strong analytical and data interpretation skills, with the ability to clearly communicate results to scientific and cross‑functional audiences.
• Consistent record of maintaining experimental rigor,…