Synthetics Supply Manufacturing Engineer

Synthetics Supply Manufacturing Engineer

Lets do this. Lets change the world. In this vital role you will join our Drug Substance and Drug product facilities in Thousand Oaks as part of its GMP and non-GMP manufacturing capabilities within the Synthetic Supply function.

We are seeking a candidate experienced in chemical engineering to join our operations team which is responsible for execution of small molecule active pharmaceutical ingredient (API) production and development of clinical formulations for solid oral drug product dosage forms. The candidate will be responsible for all aspects of small molecule manufacturing to advance Amgen’s early phase synthetic pipeline.

• Leading reaction step scale up in up to 100 L reactor trains under the supervision of the Lab Manager.
• Equipment maintenance and cleaning
• Qualification of equipment
• Creation of batch records for us in GLP / GMP campaigns
• Project management of manufacturing timelines
• Supporting the other operational needs of the facility
• The candidate will also collaborate in multi-disciplinary teams with process development chemists, formulation scientists, engineers, analysts, EH&S, Quality, F&E, maintenance, and other supporting functions.

We are all different, yet we all use our unique contributions to serve patients. The engineer professional we seek is an individual with these qualifications.

• Masters degree
• Bachelors degree and 2 years of Engineering experience
• Associates degree and 6 years of Engineering experience
• High school diploma / GED and 8 years of Engineering experience

• BS or MS in Chemical Engineering
• Alternatively, life science or related field with 5 years relevant experience
• Previous industrial hands-on experience in a GMP chemical manufacturing environment
• Strong familiarity with safe chemical handling techniques including weighing, dispensing, and packaging of chemicals, drug substance intermediates, and APIs
• In depth understanding of typical unit operations for the manufacture of synthetics drug product (i.e. granulation, roller compaction, drying, milling, blending, compression, encapsulation and film coating)
• Ability to perform preventive maintenance and troubleshooting on manufacturing equipment.
• PPE familiarity and ability to use a chemical respirator
• Experience with laboratory automation including temperature control and data logging platforms such as Delta V
• Excellent verbal and written communication skills
• Proficiency with Microsoft Word, Excel, and Power Point
• Advanced scientific/technical reading/writing skills, advanced scientific analysis skills, ability to collaborate and work in team environment
• Strong familiarity with Good Documentation Practices
• Strong interpersonal skills and a proactive leadership mindset
• Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.