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Senior Associate; In Vivo Pharmacokinetics and Drug Metabolism

Job in Thousand Oaks, Ventura County, California, 91358, USA
Listing for: Amgen
Full Time position
Listed on 2026-06-09
Job specializations:
  • Research/Development
    Clinical Research, Research Scientist, Medical Science, Medical Technologist & Lab Technician
  • Healthcare
    Clinical Research, Medical Science, Medical Technologist & Lab Technician
Job Description & How to Apply Below
Position: Senior Associate (In Vivo Pharmacokinetics and Drug Metabolism )
** Join Amgen's Mission of Serving Patients*
* At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas
-Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

** Senior Associate*
* ** What you will do*
* Let's do this. Let's change the world.

We are seeking a highly motivated, detail-oriented, and collaborative Senior Associate to support In Vivo Pharmacokinetics and Drug Metabolism - Bioanalytical (PKDM-BA) research activities within a dynamic drug discovery environment. This role is designed to work closely with and support senior scientists and experienced research team members in advancing novel therapeutic candidates across a diverse multimodality portfolio. The successful candidate will contribute to preclinical in vivo PKDM studies focused specifically on mouse and rat models while developing technical expertise within a highly collaborative research setting.

*
* Key Responsibilities:

*
* + Support senior team members in the execution of preclinical in vivo PKDM-BA studies using mouse and rat models.

+ Assist with routine handling, restraint, husbandry support, and dosing of mice and rats through multiple administration routes including intravenous (IV), oral gavage (PO), subcutaneous (SC), and intraperitoneal (IP).

+ Perform biological sample collection from rodents including blood, plasma, serum, urine, feces, and tissue specimens under the guidance of experienced scientists and study leads.

+ Conduct clinical observations, monitor rodent health and welfare, and accurately document findings in accordance with study protocols and institutional guidelines.

+ Support rodent necropsy procedures, tissue collection and processing, and basic surgical manipulations as directed by senior staff.

+ Prepare study materials, dosing formulations, laboratory supplies, and associated documentation to facilitate efficient study execution.

+ Maintain accurate, organized, and compliant experimental records and laboratory documentation.

+ Assist with laboratory organization, equipment readiness, and inventory management of research consumables and animal study supplies.

+ Adhere to institutional animal care and use guidelines, SOPs, and laboratory safety procedures.

+ Collaborate effectively with scientists, veterinarians, and laboratory staff to support research timelines and study objectives.

+ Participate in team meetings, technical training, and discussions to build technical knowledge and professional development.

+ Contribute to continuous improvement initiatives, workflow optimization, and operational excellence activities within the vivarium and laboratory environment.

** What we expect of you*
* We are all different, yet we all use our unique contributions to serve patients. The successful candidate will partner closely with senior team members, scientists, and cross-functional research teams to assist in the execution of rodent studies, biological specimen collection, dosing procedures, study preparation, and experimental documentation. This position offers valuable hands-on experience supporting PKDM, ADME, and translational research activities critical to early drug development.

*
* Basic Qualifications:

*
* + Master's degree

OR

+ Bachelor's degree with a minimum of 2 years of rodent laboratory animal research experience;

OR

+ Associate's degree with a minimum of 4 years of rodent laboratory animal research experience

+ High school diploma / GED with a minimum of 6 years of rodent laboratory animal research experience.

*
* Preferred Qualifications:

*
* + Undergraduate degree in Biology, Chemistry, Animal Science, Pharmacology, or related life science discipline.

+ Hands-on experience working with mice and rats in academic, biotechnology, or pharmaceutical research environments.

+ Experience supporting senior researchers in pharmacokinetic (PK), ADME, or bioanalytical studies in rodent models preferred.

+ Familiarity with rodent handling, restraint, dosing techniques, blood collection, and sample processing procedures.

+ Basic understanding of pharmacokinetics and the role of in vivo PK studies in…
Position Requirements
10+ Years work experience
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