Scientist Protein Engineering Organic Chemist: ADC Research & Development

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission to serve patients living with serious illnesses drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year.

Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

Our award‑winning culture is collaborative, innovative, and science‑based. If you have a passion for challenges and the opportunities that lie within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Let’s do this. Let’s change the world. In this vital role you will work at the interface of synthetic chemistry, biochemistry, and chemical biology to apply their synthetic skills in developing ADC therapeutics and cutting‑edge novel modalities.

• Design, synthesize, purify, and characterize linker‑payloads for antibody‑drug conjugates (ADCs).
• Design and generate ADCs, including conjugation, purification, and characterization to support therapeutic discovery.
• Analyze and interpret data, and communicate results through clear documentation, reports, and project updates.

We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a Researcher with these qualifications.

Doctorate degree

OR

Masters degree and 2 years of organic chemistry and laboratory experience

OR

Bachelors degree and 4 years of organic chemistry and laboratory experience

• Strong proficiency in organic synthesis and chemical methodology development
• Knowledge of, or experience with, protein conjugation and protein chemistry techniques
• A robust understanding of structural determination using NMR and MS, with proficiency in chromatographic techniques (e.g., HPLC, RP‑HPLC, ion exchange, and size‑exclusion chromatography)
• Demonstration of good lab practices, with particular attention to safety
• Strong written and verbal communication skills
• Ability to work comfortably within a team of scientists and engineers with diverse technical and cultural backgrounds.

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a total rewards plan, based on eligibility, comprising:

• A comprehensive employee benefits package, including a retirement and savings plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan
• Stock‑based long‑term incentives
• Award‑winning time‑off plans
• Flexible work models where possible. Refer to the work location type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit, you may redact or remove age‑identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Final date to receive applications:
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