Associate Scientist - Cellular Assay Development, Functional Genomics

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnesses drives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions.

As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Lets do this. Lets change the world. In this vital role you will be part of a dynamic, cross-functional team to advance target and biological discovery across Amgens therapeutic areas.

• Support the execution of functional arrayed genomic screens in advanced invitro modelsin collaboration with therapeutic area partners.
• Carry out mammalian cell culture, transfection, transduction, and functional assays toenable functional, arrayedgenomic screens; experience with iPSC culture and differentiation preferred.
• Optimize and miniaturize cell-based assays for high-throughput automated screening.
• Leverage functional assays, particularly high-content imaging,to profile cellular phenotypes and states.
• Partner with TD&B and cross-functional team members, including automation colleagues, to accelerate model deployment and reproducibility.
• Collaborate with Amgen therapeutic area scientists to define requirements, ensure biological relevance, and deliver systems that enable mechanistic and translational insights.
• Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgens pipeline.

We are all different, yet we all use our unique contributions to serve patients. The Associate Scientist we seek is a researcher with these qualifications.

Masters degree and 1 year of scientific/drug discovery experience andtrack recordof scientific excellence and productivity

OR

Bachelors degree and 3 years of scientific/drug discovery experience andtrack recordof scientific excellence and productivity

• M.S.degree in cell biology, molecular biology, biomedical engineering, or related discipline, or B.S. degree withcommensuratescientific/drug discovery experience andtrack recordof scientific excellence and productivity
• Proficiency with mammalian cell culture,including immortalized and primary lines required; experience with iPSC culture preferred
• Experience with gene editing/delivery techniques,i.e.CRISPR/Cas9, lentiviral transduction, and transient transfection
• Experience with cellular assay optimization and miniaturization;familiarity working with plate-based assays and associated equipment/automation
• Strong hands-on experience with functional assays, particularly high-content imaging
• Familiarity withhigh-throughputsreeningmetrics (e.g.Z,S/B, MSMR)
• Demonstrated ability to collaborate with cross-functional teams to translate disease biology into experimental models
• Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off…