Scientist - LC-MS Bioanalytical

Career Category

Scientific

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drive all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas
-Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier live.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist - LC-MS Bioanalytical

What you will do

Let’s do this. Let’s change the world. This lab-based role supports the design, development, validation, and implementation of robust LC-MS/MS bioanalytical methods for therapeutic modalities including small molecules, oligonucleotides, proteins, and other complex molecular entities. The initial focus is to expand discovery-stage support within PKDM-BA, while maintaining flexibility to support GLP preclinical and regulated clinical activities as needed. The role will also contribute to modernization of automation and instrumentation to improve assay throughput and sensitivity, working closely with multidisciplinary research and development teams across Amgen.

Key responsibilities include:

• Plan, execute, and document quantitative LC-MS/MS bioanalytical experiments.
• Develop and implement fit-for-purpose bioanalytical methods with rapid turnaround.
• Perform small- and large-molecule bioanalysis in nonclinical and clinical matrices, including plasma, urine, CSF, and tissues.
• Prepare biological samples using protein precipitation, solid-phase extraction, liquid-liquid extraction, affinity capture, and related techniques.
• Organize, analyze, interpret, and present bioanalytical data with strong attention to data integrity and fidelity.
• Maintain complete, accurate, and concise documentation in electronic laboratory notebooks and other laboratory systems.
• Ensure data and records meet applicable regulatory expectations for global submissions and remain current with relevant industry guidance.
• Author and review study reports, analytical methods, SOPs, technical memos, and other regulatory-compliant documents.
• Communicate bioanalytical results to discovery and development teams; contribute to publications and present findings at scientific meetings.
• Support report quality control, effective time management, and clear cross-functional communication.
• Follow all safety, training, documentation, and site-specific procedural requirements.
• Perform routine laboratory housekeeping and operational support activities as needed.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a key contributor with these qualifications.

Basic Qualifications:

Doctorate degree

Or

Master’s degree and 2 years of relevant industrial/technical experience

Or

Bachelor’s degree and 4 years of relevant industrial/technical experience

Preferred Qualifications:

• Prefer Bachelor’s or Master’s experience
• Prior experience in CRO or pharma/biotech strongly desired
• Strong technical expertise in quantitative mass spectrometry on triple quadrupole (QQQ) platforms as well as HRMS
• Experience with an array of analytical technologies that can accelerate bioanalysis inclusive of…