Organic and Conjugation Chemist

** Associate Scientist  - Organic and Conjugation Chemist*
* ** Live*
* ** This could be your everyday*
* Let's do this. Let's change the world.

The Hybrid Modality Group in the Complex Biologics & Strategic Tech Alliance Department of LMD & RDS at Amgen is seeking a highly motivated scientist in the field of chemical conjugation to join us in the state-of-the-art research facility at the Amgen headquarters campus located in Thousand Oaks, CA. The qualified candidate will work at the interface of synthetic chemistry, biochemistry, and chemical biology, and apply their chemical synthesis skills in developing new hybrid therapeutics and to support the advancement of drug discovery programs

+ Responsibilities including (but not limited to) synthesis, purification and characterization of antibody, protein, peptide conjugates for potential clinical drug development.

+ Synthesis, purification  
** and characterization of small molecule payloads and linkers for development of novel antibody-drug conjugates.*
* + Operate and maintain standard lab equipment.

+ Document experimental plans and procedures with attention to detail in a timely manner.

+  
** Review, analyze, and interpret scientific data and results; and provide regular updates, documentation, and/or communication on project results.*
* ** Win*
* ** Here's what it takes to Win*
* We are all different, yet we all use our unique contributions to serve patients. The dedicated individual we seek is a scientist with these qualifications.

** Basic qualifications*
* + Master's Degree

Or

+ Bachelor's Degree and 2+ years of relevant experience

OR

+ Associate's degree and 4 years of relevant experience

OR

+ High school diploma / GED and 6 years of relevant experience

** Preferred qualifications*
* + Master's degree in Organic Chemistry, Biochemistry, or a related field

+

Demonstrated proficiency in organic synthesis including designing, executing, and optimizing chemical reactions

+ Experience in peptide synthesis is preferred

+

Experience with protein conjugation is preferred

+ Experienced in various purification and analytical techniques including chromatography methods (e.g. HPLC, RP HPLC chromatography) and structural determination methods (e.g. NMR, MS)

+ Demonstration of good lab practices, with particular attention to safety

+ Strong written and verbal communication skills

+ Ability to work comfortably within a dynamic team of scientists and engineers with diverse technical and cultural backgrounds

** What you can expect of us*
* As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

+ A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

+ A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

+ Stock-based long-term incentives

+ Award-winning time-off plans

+ Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

** Apply now and make a lasting impact with the Amgen team.*
* ***
* In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

** Final date to receive applications*
* ** External/Internal postings:*
* Amgen does not have…