Principal Scientist
Listed on 2026-02-12
-
Science
Research Scientist, Biotechnology
We are retained by a mission-driven early-stage biotech advancing a first-in-class therapeutic oxygen carrier designed for use when blood is unavailable, including trauma and battlefield settings. The company is well-capitalised through a combination of private investment and significant non-dilutive government funding
, and is entering a critical phase of IND-enabling development
.
This is a newly created hands-on Principal Scientist role, designed to strengthen scientific execution and support the transition from advanced formulation into process development, scale-up, and CMC readiness
.
Reporting into senior scientific leadership, the Principal Scientist will play a key role in advancing the lead program toward IND by bridging laboratory execution with translational and CMC-focused activities.
This position is ideal for an experienced industry scientist who enjoys being close to the bench
, mentoring junior team members, and contributing to high-impact decision-making without carrying full executive responsibility.
- Lead and execute laboratory-based development activities across formulation, process development, and scale-up
- Support CMC strategy
, including method development, manufacturing readiness, and CDMO collaboration - Contribute to IND-enabling studies
, data generation, and documentation - Partner closely with senior scientific leadership to translate development plans into executable experiments
- Mentor and develop junior scientists, helping raise technical standards and scientific rigor
- Ideal Background
- PhD in chemical engineering, bioengineering, biochemistry, materials science, or related discipline
- Proven experience in process development and CMC-focused programs within biotech or pharma
- Strong grounding in chemical processing
; experience with complex or non-traditional therapeutics highly valued - Comfortable operating in an early-stage, fast-moving environment
- Prior IND or late preclinical experience strongly preferred
- Meaningful, life-saving technology with strong validation and funding
- High scientific ownership and visibility
- Opportunity to grow with the company as it advances toward the clinic
- Competitive compensation and equity participation
All discussions are handled in strict confidence.
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