Research Scientist III, Cellular and Molecular Medicine

Research Scientist III, Cellular and Molecular Medicine (Full-Time)

Research Scientist III, Cellular and Molecular Medicine (Full-Time)

Posting Number req
27066

Department Cellular & Molecular Medicine

Department Website Link https://cmm.arizona.edu/

Location Tucson Campus

Address 1501 N. Campbell Ave, Tucson, AZ 85719 USA

The Department of Cellular & Molecular Medicine (CMM) and the Sarver Heart Center (SHC) at the University of Arizona in Tucson, AZ, with strong support from the College of Medicine – Tucson, invite applications for a Research Scientist III position in cardiovascular molecular, cellular, and biophysics, with particular interest in conducting experiments such as cardiac slicing and cardiomyocyte contractility and calcium transients (Ion Optix), measuring pCa-force using papillary muscles (Aurora system), and performing myocardial infarction animal surgery and echocardiography.

This is a joint recruitment. The successful candidate will hold a Research Scientist III appointment in CMM and full membership in the Sarver Heart Center and will direct the day-to-day operations of the Sarver Heart Center cardiovascular physiology core facility—delivering state-of-the-art functional phenotyping services that connect molecular and cellular measurements to whole-heart function for investigators across the University of Arizona.

We seek an experienced, hands-on scientist with a strong command of cardiovascular physiology methods, a service-oriented approach, and the ability to train and support a community of investigators and trainees. Candidates holding a PhD, MD, or MD/PhD with demonstrated expertise in cardiac and skeletal muscle physiology, or a closely related experimental discipline, are encouraged to apply.

• Visa sponsorship is available for this position.

Outstanding U of A benefits include health, dental, and vision insurance plans; life insurance and disability programs; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; state retirement plan; access to UA recreation and cultural activities; and more!

The University of Arizona has been recognized for our innovative work-life programs. For more information about working at the University of Arizona and relocation services,.

• Develop, plan, design, and conduct advanced, multi-disciplinary research. Review progress and evaluate results.
• Formulate research methods, develop or collaborate in the development of new techniques, methods, and equipment.
• Recommend solutions for research methodology by interpreting principles and analyzing complex facts.

• Animal surgery :
  Induce myocardial infarction in wild-type and disease models and test small molecules for SHC members.
• Echocardiography :
  Assess cardiac function and drug responses in animal disease models for SHC members.
• Cardiomyocyte/organoid contractility:
  Measure contractility and calcium transients in isolated, iPSC-derived cardiomyocytes, and organoids using the Ion Optix System; test small molecules for SHC members.
  
  Cardiac slicing:
  Assess contractility and calcium transients in heart tissue using the Ion Optix Myo Clamp System and test small molecules for SHC members.
• pCa-force and muscle mechanics:
  Measure maximal force, myofilament calcium sensitivity, force redevelopment, and Hill coefficient in skinned papillary muscles using the Aurora System; test small molecules for SHC members.
• Data analysis, spreadsheet management, and data presentations. Assist with the maintenance of laboratory equipment and supplies inventory.
• Serve as the biosafety and chemical safety officer for the…