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Manufacturing Supervisor

Job in Tustin, Orange County, California, 92681, USA
Listing for: BioTalent
Full Time position
Listed on 2026-07-28
Job specializations:
  • Manufacturing / Production
    Pharmaceutical Manufacturing, Validation Engineer, Production Manager
Salary/Wage Range or Industry Benchmark: 110000 - 150000 USD Yearly USD 110000.00 150000.00 YEAR
Job Description & How to Apply Below

Are you an experienced Downstream Manufacturing professional ready to lead a high-performing team in biologics manufacturing?

We're seeking a Supervisor, Manufacturing Downstream to oversee purification operations, drive cGMP compliance, and support the production of innovative biopharmaceutical products.

What You’ll Do
  • Supervise downstream manufacturing operations in a GMP environment.
  • Lead chromatography, tangential flow filtration (TFF), nanofiltration, and purification activities.
  • Coordinate daily production schedules and manufacturing priorities.
  • Review Batch Records, SOPs, and manufacturing documentation.
  • Lead deviation investigations and CAPA implementation.
  • Support technology transfer and new process implementation.
  • Partner with QA, QC, Validation, and Engineering teams.
  • Mentor and develop manufacturing personnel while promoting operational excellence.
We're Looking For
  • Bachelor’s degree in Biology, Biotechnology, Chemical Engineering, or related field.
  • 3–5+ years of downstream biopharmaceutical manufacturing experience.
  • 3+ years of supervisory experience in downstream manufacturing.
  • Strong experience with chromatography, TFF/UFDF, purification, and aseptic processing.
  • Excellent knowledge of GMP documentation, deviations, and CAPAs.
  • Strong leadership, communication, and problem-solving skills.

Applicants must be authorized to work in the U.S. Sponsorship is not available.

#Biotech Jobs #Downstream Processing #Protein Purification #Chromatography #TFF #Biopharma #Manufacturing Supervisor #Life Sciences #Hiring #Tustin Jobs

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