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Sr. Manufacturing Associate – Downstream

Job in Tustin, Orange County, California, 92681, USA
Listing for: BioTalent
Per diem position
Listed on 2026-09-21
Job specializations:
  • Manufacturing / Production
    Pharmaceutical Manufacturing, Manufacturing & Industrial Operations, Validation Engineer
Salary/Wage Range or Industry Benchmark: 95000 - 130000 USD Yearly USD 95000.00 130000.00 YEAR
Job Description & How to Apply Below

Are you an experienced biologics manufacturing professional looking to contribute to the development of life-saving therapies?

s looking for a Sr. Manufacturing Associate - Downstream to join our team and support manufacturing operations within a state-of-the-art viral vector facility
.

What We're Looking For
  • BS in Biotechnology, Biology, Chemistry, Biochemistry, or related field
  • 2+ years of GMP biologics manufacturing experience
  • Previous downstream manufacturing experience is required
  • Strong knowledge of GMP, FDA/EMA requirements, and biologics manufacturing
  • Experience with viral vector manufacturing is highly preferred
  • Strong understanding of aseptic processing and cleanroom operations
  • Excellent troubleshooting, communication, documentation, and problem-solving skills
  • Previous upstream experience is a plus
  • Schedule: Monday-Friday, 8:00 AM-5:00 PM, with flexibility for overtime, weekends, and holidays as needed.
What You'll Do
  • Execute downstream manufacturing processes including harvest, clarification, TFF, chromatography, filtration, and product filling
  • Perform in-process testing including pH, osmolality, conductivity, and filter integrity testing
  • Troubleshoot equipment and manufacturing processes in partnership with MSAT
  • Execute production activities in a GMP/cGMP cleanroom environment
  • Prepare buffers and media required for manufacturing
  • Support equipment setup, material preparation, and cleanroom readiness
  • Create and revise SOPs, Batch Production Records, logbooks, deviations, and other GMP documentation
  • Train and mentor junior Manufacturing Associates
  • Participate in continuous improvement initiatives
  • Maintain high standards of aseptic technique, safety, quality, and compliance

Be part of a team working at the forefront of biopharmaceutical manufacturing and viral vector production
, while helping bring innovative therapies closer to patients.

Work Authorization:

Applicants must be authorized to work for any employer in the U.S. We are unable to sponsor or take over sponsorship of an employment Visa at this time

Position Requirements
10+ Years work experience
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