Sr. Scientist, Downstream and Biologics Formulation Development

Looking to join a passionate team dedicated to developing and manufacturing life‑saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.

Avid is seeking a highly motivated and technically strong Sr. Scientist, Downstream and Biologics Formulation Development to lead biologics formulation development while contributing to integrated downstream process development within a fast‑paced, client‑facing environment. This role is responsible for defining formulation strategies, executing technical studies, and supporting cross‑functional integration as the capability expands. Additional responsibilities include designing downstream purification processes for protein‑based biologics, viral clearance studies, scale‑down and scale‑up activities, and technology transfer to manufacturing.

The individual will collaborate closely with Cell Line Development, Upstream Process Development, Analytical Sciences, MSAT, DS/DP Manufacturing, Program Management, and external partners to support client programs.

• Lead formulation development for biologics, including pre‑formulation assessments, excipient screening, and stability studies. Demonstrated experience in formulation development for complex biologic modalities—including antibody–drug conjugates (ADCs)—with understanding of modality‑specific stability and develop ability challenges is highly advantageous.
• Lead downstream process development for biologics, including capture chromatography, polishing chromatography, viral inactivation/filtration, and tangential flow filtration (TFF).
• Extensive hands‑on experience with analytical techniques for protein characterization, including DLS, DSF, SEC, CE, rheology, and spectroscopy. Design and interpret analytical testing strategies including HPLC (SEC & IEX), CE‑SDS, SDS‑PAGE, UV spectroscopy, and other biophysical assays to support process development and formulation studies.
• Expertise in developing high concentration protein formulations and resolving issues such as aggregation, viscosity, and solubility. Able to identify and mitigate formulation risks including precipitation and chemical degradation.
• Design experiments, analyze data, and prepare technical protocols, reports, and development summaries.
• Establish and drive scientific strategy, workflows, and best practices for early‑to‑late‑stage biologics formulation development, with the ability to operate independently in a dynamic, fast‑paced, client‑facing environment with evolving priorities.
• Serve as a technical subject matter expert (SME) in client engagements, including proposals, presentations, and project reviews; prior line management or informal leadership experience is advantageous.
• Collaborate effectively with cross‑functional teams to align project timelines, priorities, and resource planning.
• Mentor and develop junior scientists and technical staff, and support onboarding of new team members.
• Evaluate and implement new technologies and platform approaches to enhance internal capabilities and drive innovation.
• Ensure compliance with applicable quality, regulatory, and safety standards.
• Perform additional responsibilities as required to support evolving business and project needs.
• Occasional travel may be required (by land or air) to attend conferences, seminars, off‑site client meetings, and marketing events as needed.

• Master’s degree/PhD degree in Biochemistry, Chemistry, or related field and minimum 4‑6 years of relevant experience and demonstrated working knowledge of scientific principles.
• Prior experience in formulation development, stability studies, and analytical characterization of biologics or strong background in biochemical and biophysical characterization of proteins with deep understanding of protein structure and function.
• Experience in development of ultra‑high concentration and pre‑develop ability assessment.
• Proven record of strong technical writing and communication skills.
• Ability to thrive in a dynamic, cross‑functional environment.

• Ph.D.…