Senior Manager, Data Sciences

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:  Insight at the Cutting Edge of Drug Development Are you a hands-on data scientist with a passion for turning complex, multi-modal data into actionable insights that shape clinical decisions?

Bristol Myers Squibb is seeking a Senior Manager, Data Science to join our Drug Development Data Science & Advanced Analytics (DSAA) team.

This is a new role for a state-of-the-art individual contributor who thrives at the interface of computational science, statistical rigour, and drug development. You will execute and drive exploratory and confirmatory analyses across a rich variety of data types — from clinical trial data to genomics, proteomics, imaging, and beyond — contributing directly to decisions that advance our global development pipeline.

What You'll DoData Science & Analytics Develop and apply novel computational methods for patient segmentation, biomarker discovery, and hypothesis generation from multimodal clinical and omics datasets, in partnership with Translational, Clinical, and Statistical Scientists Execute data science analyses on datasets from BMS clinical trials and real-world data cohorts, spanning genomics, proteomics, imaging, flow cytometry, and other high-dimensional biomarker data types

Develop innovative approaches to integrating, mining, and visualising diverse, high-dimensional, and disparate datasets generated across early-to-late phase drug development

Formulate, implement, test, and validate predictive models and build efficient, automated processes for delivering modelling results at scale

Apply modern machine learning capabilities — including AI/ML, deep learning, NLP, causal ML, and explainable AI — across multiple data modalities and clinical development contexts

Apply statistically rigorous approaches to clinical trial data, including survival analysis, longitudinal/mixed-effects modelling, and appropriate handling of missing data and censoring

Contribute to the scientific and statistical strategy of drug development programs, including the development of predictive biomarkers, novel trial designs, and precision medicine approaches

Data Engineering & Reproducibility Build and maintain well-structured, reproducible, version-controlled analytical pipelines and codebases using Python, R, SQL, and cloud platforms

Develop and apply data quality frameworks to assess and ensure fitness-for-purpose of diverse data sources for specific analytical questions

Implement strong model evaluation practices including cross-validation strategies, calibration assessment, and transparent reporting of model performance and limitations

Build scalable, automated processes for delivering analytical results across multiple programs and data types

Collaboration & Technical Contribution Partner with lead and protocol statisticians in contributing to statistical analysis plans (SAPs) for exploratory data science analyses supporting drug development programs

Collaborate with cross-functional teams including clinicians, translational medicine scientists, biostatisticians, data engineers, and IT/engineering professionals

Contribute to team excellence through code reviews, technical mentorship, and raising the overall engineering and methodological standards of the team Communicate analytical strategies and results clearly and effectively to…