Lab Assistant, Manufacturing; 2nd shift

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein.

Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics.

Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Assistant I, Manufacturing will perform basic laboratory duties involved with maintaining the cleanliness of the company’s chemical laboratories, equipment and maintaining stock levels of inventory. In addition, they will assist production chemists with routine production activities i.e., non-GMP and GMP manufacturing of oligonucleotides.

2nd shift work hours are Monday - Thursday 1pm – 11:30pm and eligible for a 10% shift differential.

• Maintain glassware for the laboratory;
• Maintain cleanliness and orderliness of work areas;
• Maintain stocks of laboratory supplies and material and maintains appropriate records;
• Follow safety procedures for chemical handling, as appropriate;
• Follow batch records, SOPS, and work instructions to detail;
• Document all operations in batch records and notebooks;
• Comply with GMP protocols;
• Assist with and support operation of large scale oligonucleotide manufacturing equipment (i.e. oligonucleotide synthesizer, purification skid, tangential flow filtration system, lyophilizer, Chem Glass reactors, pH/conductivity meters, peristaltic pumps, etc.)

• High school diploma
• Good verbal and written communication skills
• Ability to work in a team environment
• Ability to pay attention to detail

• Previous experience in a laboratory setting
• Some college or concurrent college course attendance

$40,000—$45,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.