Senior Director, Compliance Business Partner

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.Madrigal's medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH.

Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration.

To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

Madrigal Pharmaceuticals is seeking a Senior Director, Compliance Business Partner to support and enhance its global Compliance Program. This role will serve as a key advisor to business stakeholders, providing practical, risk-based compliance guidance across a range of commercial and other activities.

The Senior Director will partner cross-functionally to help ensure that business initiatives - including healthcare professional engagements, advisory boards, patient support programs, grants, and promotional and non-promotional activities - are executed in alignment with applicable laws, regulations, and company policies.

The ideal candidate will bring strong compliance and legal acumen, sound judgment, and the ability to translate complex regulatory requirements into actionable guidance in a fast-paced, evolving environment.
** Position Responsibilities
** The key responsibilities for this role include:
* Serve as a Compliance Business Partner to Commercial, Patient Advocacy, Patient Support Services, and other cross-functional stakeholders, providing proactive, risk-based guidance on business activities and strategic initiatives
* Provide compliance review and oversight of key activities, including healthcare professional engagements, advisory boards, needs assessments, internal and external meetings, patient support programs, and promotional and non-promotional materials
* Advise on business initiatives through the application of legal and compliance frameworks, including review of documentation and agreements in collaboration with Legal, as appropriate
* Support the development and delivery of compliance training and communications to promote awareness and understanding of compliance requirements
* Conduct third-party risk management activities, including due diligence, risk assessment, and ongoing oversight of vendors and partners
* Participate in governance activities, including grant committees and business reviews, providing compliance guidance to support appropriate decision-making
* Support compliance monitoring, risk assessment, and investigation activities, including identifying trends, assessing risk, and contributing to remediation efforts
* Contribute to the development and continuous improvement of compliance policies, procedures, and program infrastructure
* Communicate compliance risks, trends, and insights to leadership and relevant governance forums
** Education & Experience
*** Bachelor's degree required; advanced degree (e.g., JD, MBA, or CPA) and/or Paralegal certification or equivalent legal training/experience preferred
* 12+ years of pharmaceutical or life sciences compliance experience
* Demonstrated experience supporting commercial and/or other functions in a compliance business partner capacity
* Strong knowledge of healthcare laws, regulations, and industry codes
** Preferred Qualifications
*** Experience supporting healthcare professional engagements, advisory boards, and patient support programs
* Experience with third-party risk management and compliance due diligence
* Prior experience in a business-facing compliance role within a biopharmaceutical company
* Ability to interpret and apply regulatory requirements in a practical, business-oriented manner
** Key Competencies
*** Strong judgment and ability to balance compliance risk with business objectives
* Excellent communication and stakeholder management skills
* Ability to operate effectively in a fast-paced, cross-functional environment
* Collaborative, solutions-oriented approach to business partnering
* High level of integrity, professionalism, and accountability
* Strong analytical skills with attention to detail
* Ability to manage multiple priorities and deliver high-quality work under tight timelines
* Positive, adaptable approach with a sense of perspective and humor

Madrigal's Total Rewards strategy is based on a biotech industry peer group…