Executive Medical Director, Clinical Development Lead - Oncology - Lung & Head​/Neck Cancers

Business Introduction

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

The Clinical Development Lead (CDL) - Oncology operates at the asset level as the enterprise clinical strategy leader, accountable for defining the clinical strategy, scientific narrative, and decision framework across the asset lifecycle. The CDL owns the clinical roadmap and serves as the recognised clinical authority and visible leader for the asset’s strategic vision, shaping data‑driven, technology‑enabled clinical development.

• Define and own the clinical strategy, scientific narrative, integrated benefit‑risk position, and decision framework across the asset, ensuring a coherent and differentiated clinical position throughout the life‑cycle
• Accountable for strategic outcomes across the asset, with study‑level delivery, including design, execution, and data generation, led by Senior Scientists and programme teams within the CDL’s strategic direction
• Serve as the senior clinical strategy leader on the MDT core quad, acting as a full strategic partner to the Medicine Development Leader (MDL) and representing Clinical Development in portfolio, governance, and investment decisions
• Lead or co‑lead governance and investment presentations to senior management, translating clinical evidence into clear strategic recommendations for portfolio prioritisation and progression
• Serve as the recognised clinical authority and visible leader for the asset, ensuring its clinical vision, scientific identity, and development trajectory are clearly understood and advanced across the organisation
• Drive an integrated, end‑in‑mind approach to development, ensuring that target selection, development pathways, regulatory positioning, and commercial readiness are considered as a connected whole
• Act as the default Clinical Development representative for Health Authority interactions, advisory boards, steering committees, IDMCs, and alliance partnerships
• Leverage AI‑enabled insights, advanced analytics, and emerging data platforms to inform asset‑level strategic decisions and drive competitive advantage in development speed and decision quality
• Lead, develop, and mentor clinical development talent, contributing to talent calibration, succession planning, and capability building aligned to evolving development models

• Serve as the senior clinical strategy leader on the MDT core quad, representing the voice of Clinical Development in portfolio, governance, and investment decisions
• Own the clinical and scientific narrative for the asset, acting as the recognised clinical authority whose leadership is synonymous with the asset’s clinical vision and development trajectory
• Lead or co‑lead governance and investment discussions, translating clinical evidence and benefit‑risk into strategic recommendations that inform portfolio prioritisation and resource allocation
• Drive an integrated, end‑in‑mind approach to clinical strategy, moving beyond sequential development to ensure alignment across scientific, regulatory, and commercial considerations
• Proactively engage enterprise stakeholders – including Medical Affairs, Integrated Evidence, Commercial, and Regulatory – to integrate perspectives, resolve trade‑offs, and align on product strategy
• Define the asset‑level evidence‑generation strategy, including how clinical data is prioritised and integrated across development, regulatory, and lifecycle decisions
• Operate across the full asset life‑cycle, integrating insights across studies and functions to ensure a coherent and differentiated clinical position

• Accountable for the strategic integrity and clinical direction of the Clinical Development Plan (CDP), ensuring it reflects asset‑level strategy and is delivered through programme teams
• Own the integrated benefit‑risk framework, ensuring alignment between clinical data, safety insights, and strategic decision‑making