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Executive Director​/Vice President, Corporate Development

Job in Waltham, Middlesex County, Massachusetts, 02254, USA
Listing for: Crescent Biopharma
Full Time position
Listed on 2026-08-24
Job specializations:
  • Business
    Corporate Strategy
Salary/Wage Range or Industry Benchmark: 290000 - 320000 USD Yearly USD 290000.00 320000.00 YEAR
Job Description & How to Apply Below

Crescent Biopharma's vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company's clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies as single agents and as part of combination regimens to treat a range of solid tumors.

For more information, visit  and follow the Company on Linked In and X.

We are seeking an experienced corporate development leader to build and maintain a comprehensive view of the solid tumor oncology landscape, translate scientific and competitive intelligence into clear portfolio priorities, and identify external opportunities that can strengthen Crescent's pipeline. You will partner cross-functionally with Research, Clinical Development, Business Development, and Executive leadership to evaluate assets, inform strategic decision-making, and prepare decision-oriented recommendations for the executive team and Board.

Responsibilities
  • Landscape intelligence:
    Build and continuously maintain a comprehensive view of existing and emerging therapies across solid tumor oncology, spanning approved agents, late- and early-stage clinical assets, and preclinical modalities.
  • Portfolio matrix:
    Develop and own a matrix / portfolio view mapping our own therapies, partner therapies, and prospective in-licensing targets against tumor types, lines of therapy, mechanisms of action, and combination potential.
  • Search & evaluation:
    Proactively search for, identify, and evaluate potential opportunities (research collaboration, in-licensing preclinical and clinical assets, platform technologies and research tools) that are consistent with external BD strategies for the advancement of Crescent's Oncology pipeline, and driving sustainable growth for the Company. Review external opportunities for scientific merit and feasibility.
  • Prioritization & gap analysis:
    Identify and prioritize where partnering, collaboration, or asset in-licensing can complete or strengthen the portfolio and articulate the strategic case for each opportunity.
  • Data sourcing:
    Source, validate, and synthesize intelligence from clinical, competitive, and commercial databases to support decision-making (e.g., Clinical Trials.gov, primary literature).
  • Cross-functional partnership:
    Partner closely with Research, Clinical Development, Business Development, and Executive leadership to translate portfolio strategy into actionable prioritization and resource allocation.
  • Executive communication:
    Prepare clear, decision-oriented materials for the executive team and Board that communicate portfolio positioning, trade-offs, and recommendations.
Education & Experience
  • Advanced scientific degree strongly preferred — PhD and/or MD in a relevant discipline (oncology, immunology, molecular/cancer biology, pharmacology). Exceptional candidates with equivalent depth ofexpertiseand experience will be considered.
  • Demonstrated ability to understand and critically evaluate the mechanisms of action for oncology therapeutics
  • Minimum 12 years of experience in oncology portfolio strategy, competitive intelligence, business development, translational research, or a closely related function within biopharma.
  • Hands-on fluency with clinical-trial, pipeline, and competitive-intelligence databases, and the ability to structure disparate sources into a coherent analytical framework.
  • Proven ability to build structured frameworks (matrices, prioritization models) that turn complex scientific and competitive information into clear strategic recommendations.
  • Strong written and verbal communication; able to translate dense science into decisions for scientific and non-scientific stakeholders alike.
  • Strong analytical, strategic thinking, and problem-solving skills.
  • Excellent communication and leadership abilities; able to influence across all levels of the organization.
  • Ability to thrive in a fast-paced, ambiguous environment while managing competing priorities.
  • Commitment to fostering a diverse and inclusive workplace.
Wha…
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